DDR1 Antibody (7F6) - BSA Free

Novus Biologicals | Catalog # NBP3-26629

Recombinant Monoclonal Antibody
Novus Biologicals
100% Guarantee

Key Product Details

Species Reactivity

Human

Applications

ELISA

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Human IgG1 Clone # 7F6 expressed in HEK293

Format

BSA Free
View all DDR1 Primary Antibodies »

Product Specifications

Immunogen

Recombinant Human DDR1 protein [UniProt Q08345]

Clonality

Monoclonal

Host

Human

Isotype

IgG1

Scientific Data Images for DDR1 Antibody (7F6) - BSA Free

DDR1 Antibody (7F6)

ELISA: DDR1 Antibody (7F6) [NBP3-26629] -

ELISA: DDR1 Antibody (7F6) [NBP3-26629] - The Binding Activity of Human DDR1 with DDR1 Antibody.
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human DDR1 at 2 ug/mL can bind DDR1 Antibody, the EC50 is 2.824-3.810 ng/mL.

Applications for DDR1 Antibody (7F6) - BSA Free

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

50% Glycerol, 0.01M PBS, PH 7.4

Format

BSA Free

Preservative

0.03% Proclin 300

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20 to -70C. Avoid freeze-thaw cycles.

Background: DDR1

Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation and metabolism. The protein encoded by this gene is a RTK that is widely expressed in normal and transformed epithelial cells and is activated by various types of collagen. This protein belongs to a subfamily of tyrosine kinase receptors with a homology region to the Dictyostelium discoideum protein discoidin I in their extracellular domain. Its autophosphorylation is achieved by all collagens so far tested (type I to type VI). In situ studies and Northern-blot analysis showed that expression of this encoded protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, this protein is significantly over-expressed in several human tumors from breast, ovarian, esophageal, and pediatric brain. This gene is located on chromosome 6p21.3 in proximity to several HLA class I genes. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq]

Long Name

Discoidin Domain Receptor 1

Alternate Names

CAK, CD167a, RTK6, TrkE

Gene Symbol

DDR1

Additional DDR1 Products

Product Documents for DDR1 Antibody (7F6) - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for DDR1 Antibody (7F6) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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FAQs for DDR1 Antibody (7F6) - BSA Free

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  • Q: I was wondering if you offer, or are planning on offering, any antibodies targeted to specific phosphorylation sites on the receptor tyrosine kinase DDR1.

    A: At this time we do not offer and DDR1 antibodies specific for certain phosphorylation states.

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