Desmoglein-2 Antibody (23GB5215)

Novus Biologicals | Catalog # NBP3-51338

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Western Blot, Flow Cytometry, Knockdown Validated

Label

Unconjugated

Antibody Source

Monoclonal Rabbit IgG Clone # 23GB5215
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Product Specifications

Immunogen

A synthesized peptide derived from human Desmoglein-2 (Uniprot: Q14126)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Desmoglein-2 Antibody (23GB5215)

Desmoglein-2 Antibody (23GB5215)

Flow Cytometry: Desmoglein-2 Antibody (23GB5215)[NBP3-51338] -

Flow cytometric analysis of Desmoglein-2expression in HepG2 cells using Desmoglein-2 antibody (1:2,000). Green, isotype control; red, Desmoglein 2.
Desmoglein-2 Antibody (23GB5215)

Western Blot: Desmoglein-2 Antibody (23GB5215)[NBP3-51338] -

Western blotting analysis using Desmoglein-2 antibody (1:5,000) and HRP-conjugated goat anti-rabbit secondary antibody (1:20,000) respectively. Image was developed using FeQ(TM) ECL Substrate Kit.

Applications for Desmoglein-2 Antibody (23GB5215)

Application
Recommended Usage

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Knockdown Validated

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

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Advanced Features

  • Spectra Viewer - Custom analysis of spectra from multiple fluorochromes
  • Spillover Popups - Visualize the spectra of individual fluorochromes
  • Antigen Density Selector - Match fluorochrome brightness with antigen density
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Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.4), 50% glycerol

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Desmoglein-2

Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Desmoglein 2 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This second family member is expressed in colon, colon carcinoma, and other simple and stratified epithelial-derived cell lines.

Alternate Names

CDHF5, Desmoglein2, DSG2, HDGC

Gene Symbol

DSG2

Additional Desmoglein-2 Products

Product Documents for Desmoglein-2 Antibody (23GB5215)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Desmoglein-2 Antibody (23GB5215)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

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