HDAC5 Antibody

Novus Biologicals | Catalog # NBP2-03988

Novus Biologicals
Discontinued Product
NBP2-03988 has been discontinued. View all Histone Deacetylase 5/HDAC5 products.

Key Product Details

Species Reactivity

Human, Mouse

Applications

Western Blot, Immunoprecipitation, Chromatin Immunoprecipitation (ChIP)

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG
View all Histone Deacetylase 5/HDAC5 Primary Antibodies »

Product Specifications

Immunogen

This antibody was generated by immunizing rabbits with a synthetic peptide corresponding to amino acids 572-596 of human HDAC-5.

Reactivity Notes

Human and Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for HDAC5 Antibody

Western Blot: 0 [NBP2-03988]

Western Blot: 0 [NBP2-03988]

Western Blot: HDAC5 Antibody [NBP2-03988] - Analysis of HDAC-5 in NIH 3T3 cell lysate using this antibody at 2 ug/ml.

Applications for HDAC5 Antibody

Application
Recommended Usage

Chromatin Immunoprecipitation (ChIP)

1:10-1:500

Immunoprecipitation

1:10-1:500

Western Blot

1-3 ug/ml
Application Notes
Chromatin Immunoprecipitation: Refer to Imbriano (2005, Fig 7) for details.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

0.2 ml PBS

Preservative

0.05% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Histone Deacetylase 5/HDAC5

Histone deacetylase (HDAC) and histone acetyltransferase (HAT) are enzymes that regulate transcription by selectively deacetylating or acetylating the eta-amino groups of lysines located near the amino termini of core histone proteins. Eight members of HDAC family have been identified in the past several years. These HDAC family members are divided into two classes, I and II. Class I of the HDAC family comprises four members, HDAC-1, 2, 3, and 8, each of which contains a deacetylase domain exhibiting from 45 to 93% identity in amino acid sequence. Class II of the HDAC family comprises HDAC-4, 5, 6, and 7, the molecular weights of which are all about twofold larger than those of the class I members, and the deacetylase domains are present within the C-terminal regions, except that HDAC-6 contains two copies of the domain, one within each of the N-terminal and C-terminal regions. Human HDAC-1, 2 and 3 were expressed in various tissues, but the others (HDAC-4, 5, 6, and 7) showed tissue-specific expression patterns. These results suggested that each member of the HDAC family exhibits a different, individual substrate specificity and function in vivo.

Long Name

Histone Deacetylase 5

Alternate Names

FLJ90614, KIAA0600, NY-CO-9

Gene Symbol

HDAC5

UniProt

NP_001015053 (Human)

Additional Histone Deacetylase 5/HDAC5 Products

Product Documents for HDAC5 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for HDAC5 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

Adult Neurogenesis
Epigenetics

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