HLA G Antibody (MEM-G/1) - BSA Free

Immunohistochemistry: HLA G Antibody (MEM-G/1) - BSA Free [NB500-302]

Immunohistochemistry: HLA G Antibody (MEM-G/1) [NB500-302] - Fig. 1. Immunohistochemistry staining with anti-human HLA-G (MEM-G/1). Fig. 1A - pulmonary disseases (paraffin-embedded sections) The antibody MEM-G/1 stains infiltrating macrophages in pulmonary diseases. In the top left corner see the detail of macrophage.

Immunohistochemistry: HLA G Antibody (MEM-G/1) - BSA Free [NB500-302] -

Immunohistochemistry: HLA G Antibody (MEM-G/1) - BSA Free [NB500-302] - ELA affects first trimester placental explant trophoblast proliferation. (a) HLA-G immunostaining (brown color top panel) indicates the location of extravillous trophoblasts. PhosphoH3(Ser10) immunostaining (brown color lower 3 panels) identifies proliferating cells undergoing mitosis. In extravillous trophoblasts of explants treated with ELA proliferation appears to decrease. In control explants almost all villous cytotrophoblasts proliferate, while this is much less apparent in explants treated with ELA. Treatment with ELA in combination with ML221 does not return villous cytotrophoblast proliferation to the level as seen in control explants. (b) Quantifying the percentage of proliferating extravillous trophoblasts observed by immunohistochemistry shows a significant decrease upon treatment with ELA which cannot be rescued by the addition of ML221. P = 0.08 between controls & explants treated with ELA & ML221. n = 12 placentas, 5 explants per treatment. Bars represent mean ± SEM & data was tested with one-way ANOVA followed by Bonferroni multiple comparisons test. *Indicates p < 0.05. (c) Treatment of explants with an ELA neutralizing antibody shows a significant increase of extravillous trophoblast proliferation upon quantifying immunohistochemistry stainings. n = 4 placentas, 5 explants per treatment. Bars represent mean ± SEM & data was tested with a Student’s t-test. *Indicates p < 0.05. Image collected & cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/31836787), licensed under a CC-BY license. Not internally tested by Novus Biologicals.