HMGA2 Antibody

Novus Biologicals | Catalog # NBP1-51985

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Canine (100%). Backed by our 100% Guarantee.

Applications

Western Blot, Peptide ELISA

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG
View all HMGA2 Primary Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-KAAQKKAEATGEK corresponding to internal region according to NP_003474.1, NP_003475.1.

Specificity

This antibody is expected to recognize both reported isoforms (NP_003474.1; NP_003475.1) and is not expected to cross-react with HMGA1.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Description

This product may not be purchased or sold within the European Union. Please contact customer service with any questions.

Scientific Data Images for HMGA2 Antibody

Western Blot: HMGA2 Antibody [NBP1-51985]

Western Blot: HMGA2 Antibody [NBP1-51985]

Western Blot: HMGA2 Antibody [NBP1-51985] - (1ug/ml) staining of Human Heart lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Applications for HMGA2 Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:8000

Western Blot

1 - 3 ug/ml
Application Notes
WB: Approx. 18 kDa band observed in human heart lysates is reported in scientific literature (PMID: 18505920).

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: HMGA2

This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Long Name

High Mobility Group AT-hook 2

Alternate Names

BABL, HMGIC, LIPO

Entrez Gene IDs

8091 (Human)

Gene Symbol

HMGA2

UniProt

P52926

Additional HMGA2 Products

Product Documents for HMGA2 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for HMGA2 Antibody

This product may not be purchased or sold within the European Union. Please contact customer service with any questions.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

Transcription Factors

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