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Human MALT1 Antibody (MALT1-C)

R&D Systems | Catalog # MAB4850

R&D Systems

Key Product Details

Species Reactivity

Human

Applications

Western Blot, Simple Western

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # MALT1-C
View all MALT1 Primary Antibodies »

Product Specifications

Immunogen

Recombinant human MALT1
Asp701-Thr808
Accession # Q9UDY8

Specificity

Detects human MALT1 in Western blots.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for Human MALT1 Antibody (MALT1-C)

Detection of Human MALT1 antibody by Western Blot.

Detection of Human MALT1 by Western Blot.

Western blot shows lysates of Jurkat human acute T cell leukemia cell line and Daudi human Burkitt's lymphoma cell line. PVDF membrane was probed with 1 µg/mL of Mouse Anti-Human MALT1 Monoclonal Antibody (Catalog # MAB4850) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # HAF007). A specific band was detected for MALT1 at approximately 100 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 2.
Detection of Human MALT1 antibody by Simple WesternTM.

Detection of Human MALT1 by Simple WesternTM.

Simple Western lane view shows lysates of Jurkat human acute T cell leukemia cell line and Daudi human Burkitt's lymphoma cell line, loaded at 0.2 mg/mL. A specific band was detected for MALT1 at approximately 98 kDa (as indicated) using 10 µg/mL of Mouse Anti-Human MALT1 Monoclonal Antibody (Catalog # MAB4850). This experiment was conducted under reducing conditions and using the 12-230 kDa separation system.

Applications for Human MALT1 Antibody (MALT1-C)

Application
Recommended Usage

Simple Western

10 µg/mL
Sample: Jurkat human acute T cell leukemia cell line and Daudi human Burkitt's lymphoma cell line

Western Blot

1 µg/mL
Sample: Jurkat human acute T cell leukemia cell line and Daudi human Burkitt's lymphoma cell line

Reviewed Applications

Read 2 reviews rated 5 using MAB4850 in the following applications:

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: MALT1

Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT1) is an approximately 91 kDa intracellular adaptor protein that forms a complex with Bcl10 and CARMA-1. The caspase-like domain of MALT1 cleaves Bcl10 and the NF kappa B inhibitor A20. This results in NF kappa B activation following signal transduction from cell surface ITAM-containing receptors including the T cell and B cell antigen receptors. Human MALT1 shares 87% aa sequence identity with mouse and rat MALT1.

Long Name

Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1

Alternate Names

MLT1, Paracaspase

Entrez Gene IDs

10892 (Human); 240354 (Mouse); 307366 (Rat)

Gene Symbol

MALT1

UniProt

Q9UDY8 (Human)

Additional MALT1 Products

Product Documents for Human MALT1 Antibody (MALT1-C)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Note: Certificate of Analysis not available for kit components.

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Product Specific Notices for Human MALT1 Antibody (MALT1-C)

For research use only

Related Research Areas

C-type Lectin Receptors
NFkB Pathway

Customer Reviews for Human MALT1 Antibody (MALT1-C) (2)

5 out of 5
2 Customer Ratings
5 Stars
100%
4 Stars
0%
3 Stars
0%
2 Stars
0%
1 Stars
0%

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  • Human MALT1 Antibody
    Name: Anonymous
    Application: Western Blot
    Sample Tested: Aperipheral blood mononuclear cells
    Species: Human
    Verified Customer | Posted 09/14/2021
    Human MALT1 Antibody (MALT1-C) MAB4850
  • Human MALT1 Antibody
    Name: Anonymous
    Application: Western Blot
    Sample Tested: Macrophage cell lysate
    Species: Human
    Verified Customer | Posted 07/12/2021
    Human MALT1 Antibody (MALT1-C) MAB4850

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