IL-17F Antibody (4H1629.1) - BSA Free

Novus Biologicals | Catalog # NBP2-27327

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # 4H1629.1

Format

BSA Free
View all IL-17F Primary Antibodies »

Product Specifications

Immunogen

Full-length recombinant MRkIPkVGHT FFQkPESCPP VPGGSMkLDI GIINENQRVS MSRNIESRST SPWNYTVTWD PNRYPSEVVQ AQCRNLGCIN AQGkEDISMN SVPIQQETLV VRRkHQGCSV SFQLEkVLVT VGCTCVTPVI HHVQ

Reactivity Notes

The human IL17F protein shows 60% sequence similarity with Rat and 57% with Mouse, and in our testing this antibody did not react with Rat or Mouse recombinant IL17F proteins.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Scientific Data Images for IL-17F Antibody (4H1629.1) - BSA Free

Western Blot: IL-17F Antibody (4H1629.1)BSA Free [NBP2-27327]

Western Blot: IL-17F Antibody (4H1629.1)BSA Free [NBP2-27327]

Western Blot: IL-17F Antibody (4H1629) [NBP2-27327] - Analysis on full-length recombinant IL-17F proteins of (1) Human, (2) Mouse and (3) Rat using IL-17F antibody (clone 4H1629) at a concentration of 0.5 ug/ml. Note: This antibody did not detect the mouse or rat -IL-17F recombinant proteins.
Immunohistochemistry-Paraffin: IL-17F Antibody (4H1629.1) - BSA Free [NBP2-27327]

Immunohistochemistry-Paraffin: IL-17F Antibody (4H1629.1) - BSA Free [NBP2-27327]

Immunohistochemistry-Paraffin: IL-17F Antibody (4H1629) [NBP2-27327] - Detection IL-17F protein in a tissue section of human lymph node cancer using IL-17F antibody (clone 4H1629) at a concentration of 5 ug/ml.
Immunohistochemistry-Paraffin: IL-17F Antibody (4H1629.1) - BSA Free [NBP2-27327]

Immunohistochemistry-Paraffin: IL-17F Antibody (4H1629.1) - BSA Free [NBP2-27327]

Immunohistochemistry-Paraffin: IL-17F Antibody (4H1629) [NBP2-27327] - Analysis of IL-17F in formalin-fixed paraffin-embedded human colon tissue using an isotype control (top left) and IL-17F antibody (bottom left and right) at 5 ug/ml concentration.
Immunohistochemistry-Paraffin: IL-17F Antibody (4H1629.1) - BSA Free [NBP2-27327]

Immunohistochemistry-Paraffin: IL-17F Antibody (4H1629.1) - BSA Free [NBP2-27327]

Immunohistochemistry-Paraffin: IL-17F Antibody (4H1629) [NBP2-27327] - Detection -IL-17F protein in a tissue section of normal human stomach using IL-17F antibody (clone 4H1629) at a concentration of 5 ug/ml. Cytoplasmic expression was observed all over the tissue section and the staining was found to be more intense expecially in the chief cells of the glands.
Immunohistochemistry-Paraffin: IL-17F Antibody (4H1629.1) - BSA Free [NBP2-27327]

Immunohistochemistry-Paraffin: IL-17F Antibody (4H1629.1) - BSA Free [NBP2-27327]

Immunohistochemistry-Paraffin: IL-17F Antibody (4H1629) [NBP2-27327] - Detection IL17F protein in a tissue section of human stomach cancer using IL17F antibody (clone 4H1629) at a concentration of 5 ug/ml. Diffused cytoplasmic staining was observed in the tissue section and interestingly, the expression levels in cancerous tissue were found to be weaker than the parallel stained normal tissue section.

Applications for IL-17F Antibody (4H1629.1) - BSA Free

Application
Recommended Usage

Immunohistochemistry

5 ug/ml

Immunohistochemistry-Paraffin

5 ug/ml

Western Blot

0.5-2ug/ml~

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Format

BSA Free

Preservative

0.05% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: IL-17F

Interleukin 17 (IL-17) is a pro-inflammatory cytokine produced by a subset of T helper cells that develops distinct from the Th1- and Th2- cell differentiation pathways. IL-17, also known as CTLA-8, stimulates induction of other pro-inflammatory cytokines TNF alpha, IL-1 beta, IL-6, and IL-8, and reports strongly suggest the involvement of IL-17 in several chronic inflammatory diseases such as rheumatoid arthritis, psoriasis and multiple sclerosis. TGF-Beta (differentiation) and IL-23 (expansion) are required for induction and maintenance of Th17 (IL-17 producing) cells, which in turn induce the other pro-inflammatory cytokines. IL-17 (~32kDa) protein is produced and exists as a homo-dimer, has homology to a herpes virus early protein, is one of the six members (IL-17A-F) of this cytokine family, and is well characterzed and highly expressed by activated effector memory T cells.

Long Name

Interleukin 17F

Alternate Names

IL17F

Entrez Gene IDs

112744 (Human)

Gene Symbol

IL17F

UniProt

Q96PD4

Additional IL-17F Products

Product Documents for IL-17F Antibody (4H1629.1) - BSA Free

Certificate of Analysis

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Product Specific Notices for IL-17F Antibody (4H1629.1) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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