Integrin alpha 4 beta 7/LPAM-1 Antibody (CL11293) - Azide and BSA Free

Name: Integrin alpha 4 beta 7/LPAM-1 Antibody (CL11293) - Azide and BSA Free
Brand: Novus Biologicals
SKU: NBP3-44276
Price: 569 USD
Availability: InStock

Novus Biologicals | Catalog # NBP3-44276

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Product Specifications
Scientific Data
Applications
Preparation & Storage
Calculators
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG₁ Clone # CL11293

Format

Azide and BSA Free

View all Integrin alpha 4 beta 7/LPAM-1 Primary Antibodies »

Product Specifications

Immunogen

This antibody was generated using a synthetic peptide of P13612, with the exact immunogen sequence remaining proprietary.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG₁

Scientific Data Images

Western Blot: Integrin alpha 4 beta 7/LPAM-1 Antibody [NBP3-44276]

Analysis in human cell line MOLT-4.

Applications

Application

Recommended Usage

Western Blot

1 ug/ml

Formulation, Preparation, and Storage

Purification

Protein A purified

Reconstitution

Centrifuge the vial of lyophilized antibody at 12,000 x g for 20 seconds. Reconstitute by adding sterile, distilled water to achieve a final antibody concentration of 1mg/ml.

Formulation

Lyophilized from a 0.2 um filtered solution in PBS with Trehalose

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

LYOPH mg/ml

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

Background: Integrin alpha 4 beta 7/LPAM-1

The lymphocyte Peyer's patch adhesion molecule (LPAM-1), also known as integrin alpha4beta7, is a member of the integrin family of cell surface receptors. It is expressed primarily on mucosal lymphocytes, but is also present on NK cells and eosinophils. The alpha4beta7 heterodimer mediates the binding of lymphocytes to its ligand, mucosal vascular addressin (MAdCAM-1) on the high endothelial venules, thereby directing the homing of lymphocytes into Peyer's patches and intestinal lamina propria. (1-4) The monoclonal antibody DATK32 recognizes a conformational epitope on the heterodimer. (1,2)

Alternate Names

CD49d/beta7, LPAM-1, LPAM1

Gene Symbol

ITGA4

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Certificate of Analysis

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Product Specific Notices

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.