MICL/CLEC12A Antibody

Novus Biologicals | Catalog # NBP2-27346

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Predicted:

Chimpanzee (94%). Backed by our 100% Guarantee.

Applications

Validated:

Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG
View all MICL/CLEC12A Primary Antibodies »

Product Specifications

Immunogen

A portion of amino acids170-220 from human CLEC12A was used as the immunogen.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for MICL/CLEC12A Antibody

Western Blot: MICL/CLEC12A Antibody [NBP2-27346]

Western Blot: MICL/CLEC12A Antibody [NBP2-27346]

Western Blot: MICL/CLEC12A Antibody [NBP2-27346] - Analysis of CLEC12A using CLEC12A antibody. ThP1 cell lysate in the 1) absence and 2) presence of immunizing peptide probed with 2 ug/ml of CLEC12A antibody. I goat anti-rabbit Ig HRP secondary antibody and PicoTect ECL substrate solution were used for this test.

Applications for MICL/CLEC12A Antibody

Application
Recommended Usage

Western Blot

2-4ug/ml

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS and 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: MICL/CLEC12A

CLEC12A is also known as MICL or Myeloid inhibitory C-type lectin receptor, and is a member of the C-type lectin receptor superfamily (1). C-type lectins are important innate immune receptors detecting PAMPs and enhancing antigen specific responses among a very diverse role. Often lectins may enhance cell-cell interactions and also mediate pathogen recognition using C-type lectin receptors (2). CLEC12A expression has been found in normal myeloid cells and in acute myeloid leukemia cells, neutrophils, eosinophils, monocytes and dendritic cells. CLEC12A has also been found to act as an enhancer of immune responses - CLEC12A monoclonal antibody enhances specific antibody responses (3).

Long Name

Myeloid Inhibitory C-type Lectin-like Receptor

Alternate Names

CD371, CLEC12A, CLL-1, DCAL-2

Gene Symbol

CLEC12A

UniProt

Q5QGZ9

Additional MICL/CLEC12A Products

Product Documents for MICL/CLEC12A Antibody

Certificate of Analysis

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Product Specific Notices for MICL/CLEC12A Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations for MICL/CLEC12A Antibody

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