SAHA-FITC

Tocris Bioscience | Catalog # 7970

Fluorescent HDAC1/2 probe; suitable for use in TR-FRET and FP assays
Tocris Bioscience
Discontinued Product
7970 has been discontinued. View all Fluorescent Probes products.

Key Product Details

Description

Fluorescent HDAC1/2 probe; suitable for use in TR-FRET and FP assays

Wavelength

Excitation = 495 nm, Emission = 525 nm
View all Fluorescent Probes »

Product Description

SAHA-FITC is a fluorescent HDAC1/2 probe for use as a TR-FRET acceptor for CoraFluor labeling and in fluorescence polarization binding assays. Binds non-selectively to HDAC1 and HDAC2 (Kd values are 56 nM and 132 nM respectively; Ki = 1.5 nM).

Optical Data

SAHA-FITC Dye Spectra
Emission Color Green
λabs 495 nm
λem 525 nm

Spectra Viewer

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Product Specifications for SAHA-FITC

Molecular Weight

682.75

Formula

C36H34N4O8S

Storage

Store at -20°C

Purity

≥90% (HPLC)

Chemical Name

2-(6-Hydroxy-3-oxo-3H-xanthen-9-yl)-5-(3-(4-(8-(hydroxyamino)-8-oxooctanamido)benzyl)thioureido)benzoic acid

CAS Number

1160823-10-8

PubChem ID

44123666

InChI Key

GQKWRDWQZXNRAB-UHFFFAOYSA-N

SMILES

OC(C=C1OC2=C3)=CC=C1C(C4=CC=C(NC(NCC5=CC=C(NC(CCCCCCC(NO)=O)=O)C=C5)=S)C=C4C(O)=O)=C2C=CC3=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 6.83 10

Preparing Stock Solutions for SAHA-FITC

The following data is based on the product molecular weight 682.75.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 14.65 mL 73.23 mL 146.47 mL
0.5 mM 2.93 mL 14.65 mL 29.29 mL
1 mM 1.46 mL 7.32 mL 14.65 mL
5 mM 0.29 mL 1.46 mL 2.93 mL

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Background References

References are publications that support the biological activity of the product.

Product Documents for SAHA-FITC

Certificate of Analysis

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Product Specific Notices for SAHA-FITC

For research use only

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