SRGAP1 Antibody - BSA Free

Novus Biologicals | Catalog # NB100-60649

Novus Biologicals
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Key Product Details

Validated by

Independent Antibodies

Species Reactivity

Human

Applications

Immunoprecipitation

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all SRGAP1 Primary Antibodies »

Product Specifications

Immunogen

The immunogen recognized by this antibody maps to a region between residue 825 and 875 of human SLIT-ROBO Rho GTPase activating protein 1 (Rho GTPase-activating protein 13) using the numbering given in entry NP_065813.1 (GeneID 57522).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for SRGAP1 Antibody - BSA Free

Immunoprecipitation: SRGAP1 Antibody [NB100-60649]

Immunoprecipitation: SRGAP1 Antibody [NB100-60649]

Immunoprecipitation: SRGAP1 Antibody [NB100-60649] - Detection of Human SRGAP1 by Western Blot of Immunoprecipitates. Samples: Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-SRGAP1/ARHGAP13 antibody NB100-60649 5Aused for IP at 3 mcg/mg lysate. SRGAP1/ARHGAP13 was also immunoprecipitated by rabbit anti-SRGAP1/ARHGAP13 antibody NB100-60650, which recognizes a downstream epitope. Detection: Chemiluminescence with an exposure time of 1 second.

Applications for SRGAP1 Antibody - BSA Free

Application
Recommended Usage

Immunoprecipitation

2- 5 ug/mg lysate

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris-Citrate/Phosphate (pH 7.0 - 8.0)

Format

BSA Free

Preservative

0.09% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: SRGAP1

SRGAP1/ARHGAP13 is a member of the srGAP family of proteins that contain a RhoGAP domain, an SH3 domain, and a Fes/CIP4 homology domain and interact with the intracellular domain of roundabout 1 (Robo1). Robo1 is the receptor for Slit signaling and is involved in neuronal cell migration and axon tract positioning. SRGAP1/ARHGAP13 functions to bind and decrease the level of active Cdc42 and RhoA small GTPases during Slit-Robo signaling. Alternate names for SRGAP1/ARHGAP13 include Rho GTPase-activating protein 13, and KIAA1304.

Alternate Names

ARHGAP13srGAP1, FLJ22166, KIAA1304SLIT-ROBO Rho GTPase-activating protein 1, Rho GTPase-activating protein 13, SLIT-ROBO Rho GTPase activating protein 1

Entrez Gene IDs

57522 (Human)

Gene Symbol

SRGAP1

UniProt

NP_065813.1 (Human)

Additional SRGAP1 Products

Product Documents for SRGAP1 Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for SRGAP1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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