TAO Kinase 1 Antibody (24GB2320)

Novus Biologicals | Catalog # NBP3-50621

Novus Biologicals
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Western Blot, Flow Cytometry, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Monoclonal Rabbit IgG Clone # 24GB2320
View all TAO Kinase 1 Primary Antibodies »

Product Specifications

Immunogen

A synthesized peptide derived from human TAO Kinase 1 (Uniprot: Q7L7X3)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for TAO Kinase 1 Antibody (24GB2320)

TAO Kinase 1 Antibody (24GB2320)

Immunocytochemistry/ Immunofluorescence: TAO Kinase 1 Antibody (24GB2320)[NBP3-50621] -

Immunocytochemical staining of HepG2 cells with TAO Kinase 1 antibody (1:1,000). Nuclei were stained blue with DAPI; TAO Kinase 1 was stained magenta with Alexa Fluor(R) 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: Medium. Scale bar, 20 um.
TAO Kinase 1 Antibody (24GB2320)

Flow Cytometry: TAO Kinase 1 Antibody (24GB2320)[NBP3-50621] -

Flow cytometric analysis of TAO Kinase 1expression in HepG2 cells using TAO Kinase 1 antibody (1:2,000). Green, isotype control; red, TAO kinase 1.
TAO Kinase 1 Antibody (24GB2320)

Western Blot: TAO Kinase 1 Antibody (24GB2320)[NBP3-50621] -

Western blotting analysis using TAO Kinase 1 antibody (1:5,000) and HRP-conjugated goat anti-rabbit secondary antibody (1:20,000) respectively. Image was developed using FeQ(TM) ECL Substrate Kit.

Applications for TAO Kinase 1 Antibody (24GB2320)

Application
Recommended Usage

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

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Flow Cytometry

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.4), 50% glycerol

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: TAO Kinase 1

TAOK1, a member of the Ste20 kinase family, is a TAO type protein kinase that acts as an upstream activator to MARK by phosphorylation. When activated, MARK enhances microtubule dynamics and leads to phosphorylation and detachment of tau or equivalent MAPs from microtubules. Overexpression of MARK eventually leads to microtubule breakdown and cell death, but in neuronal cells the primary effect is to allow the development of neurites during differentiation.

Long Name

Serine/threonine-protein kinase TAO1

Alternate Names

hKFC-B, hTAOK1, KIAA1361, MAP3K16, MARK Kinase, MARKK, PSK-2, PSK2, TAOK1

Gene Symbol

TAOK1

Additional TAO Kinase 1 Products

Product Documents for TAO Kinase 1 Antibody (24GB2320)

Certificate of Analysis

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Product Specific Notices for TAO Kinase 1 Antibody (24GB2320)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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FAQs

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