TLR10 Antibody (3C10C5) - BSA Free

Name: TLR10 Antibody (3C10C5) - BSA Free
Brand: Novus Biologicals
SKU: NBP1-70343
Price: 169 USD
Availability: InStock

Novus Biologicals | Catalog # NBP1-70343

Submit a review

Citations (1)

Product Documents

View Available Conjugates View Available Formulations

100% Guarantee

Product Specifications
Scientific Data
Applications
Flow Cytometry
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species Reactivity

Human

Applications

Flow Cytometry, Flow (Cell Surface)

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG₁ kappa Clone # 3C10C5

Format

BSA Free

View all TLR10 Primary Antibodies »

Product Specifications

Immunogen

A partial recombinant protein containing amino acids 20-474 (extracellular domain) of human TLR10.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG₁ kappa

Scientific Data Images for TLR10 Antibody (3C10C5) - BSA Free

Flow Cytometry: TLR10 Antibody (3C10C5) [NBP1-70343]

Flow Cytometry: TLR10 Antibody (3C10C5) [NBP1-70343] - Analysis using the Alexa Fluor (R) 647 conjugate of NBP2-27214. Detection of TLR10 on human PBMC using 10 ul (1 ug) of TLR10 antibody and 1 ug of CD19 antibody. Image using the Azide Free format of this antibody.

Flow Cytometry: TLR10 Antibody (3C10C5) [NBP1-70343]

Flow Cytometry: TLR10 Antibody (3C10C5) [NBP1-70343] - Analysis using the PE conjugate of NBP2-27214. Staining of Human PBMC were probed using 10 ul (1 ug) of TLR10 antibody and 1 ug of CD19 antibody.

Applications for TLR10 Antibody (3C10C5) - BSA Free

Application

Recommended Usage

Flow Cytometry

1:10-1:1000

Flow Cytometry Panel Builder

Bio-Techne Knows Flow Cytometry

Save time and reduce costly mistakes by quickly finding compatible reagents using the Panel Builder Tool.

Advanced Features

Spectra Viewer - Custom analysis of spectra from multiple fluorochromes
Spillover Popups - Visualize the spectra of individual fluorochromes
Antigen Density Selector - Match fluorochrome brightness with antigen density

Build Your Panel Now

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Format

BSA Free

Preservative

0.05% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: TLR10

Toll-like receptors (TLRs) are one of the mechanisms by which the innate immune system senses the invasion of pathogenic microorganisms (reviewed in 1). TLRs are primary transmembrane proteins of immune cells; they have an extracellular region which contains leucine-rich repeat motifs, and a cytoplasmic tail, which has a Toll/interleukin-1 (IL-1) receptor (TIR) domain. TLRs are pattern recognition receptors (PRRs ) that bind to pathogen-associated molecular patterns (PAMPs). Different TLRs recognize different surface and intracellular components of microorganisms or PAMPS. The interaction between a TLR and a microbial component or PAMP triggers the activation of the innate immune system, as well as the development of acquired immunity. Interaction of PAMPs with different TLRs induces distinct patters of gene expression through signal transduction pathways. TLR signaling occurs through the TIR domains which utilize adaptors such as MyD88, TIRAP, TRIF, and TRAM. NF-kapppa-B and JNK pathways are activated leading to the transcription of genes encoding pro-inflammatory cytokines. TLR-10, originally identified from a spleen cDNA library, is on chromosome 4p14 and has been found to be expressed in lung and in B-lymphocytes (2). TLR10 is thought to be a potential asthma candidate gene because early life innate immune responses to ubiquitous inhaled allergens and PAMPs may influence asthma susceptibility.

Long Name

Toll-like Receptor 10

Alternate Names

CD290

Gene Symbol

TLR10

UniProt

Q9BXR5

Additional TLR10 Products

Product Documents for TLR10 Antibody (3C10C5) - BSA Free

Download Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for TLR10 Antibody (3C10C5) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.