TR alpha/NR1A1/Thyroid Hormone Receptor alpha Antibody (JE40-49)

Novus Biologicals | Catalog # NBP3-33015

Recombinant Monoclonal Antibody
Novus Biologicals
100% Guarantee

Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # JE40-49 expressed in HEK293
View all TR alpha/NR1A1 Primary Antibodies »

Product Specifications

Immunogen

Synthetic peptide within Human TR alpha/NR1A1/Thyroid Hormone Receptor alpha aa 416-465 / 490. (Uniprot: P10827)

Localization

Nucleus; Cytoplasm, Nucleus.

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

55 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for TR alpha/NR1A1/Thyroid Hormone Receptor alpha Antibody (JE40-49)

TR alpha/NR1A1/Thyroid Hormone Receptor alpha Antibody (JE40-49) Western Blot: TR alpha/NR1A1/Thyroid Hormone Receptor alpha Antibody (JE40-49) [NBP3-33015]

Western Blot: TR alpha/NR1A1/Thyroid Hormone Receptor alpha Antibody (JE40-49) [NBP3-33015]

Western blot analysis on different lysates with NBP3-33015 at 1/1,000 dilution. Lane 1: A431 cell lysate Lane 2: SW480 cell lysate Lysates/proteins at 20 µg/Lane. Predicted band size: 55 kDa Observed band size: 55 kDa Exposure time: 3 minutes; 4-20% SDS-PAGE gel. Proteins were transferred to a PVDF membrane and blocked with 5% NFDM/TBST for 1 hour at room temperature. NBP3-33015 at 1/1,000 dilution was used in 5% NFDM/TBST at room temperature for 2 hours. Goat Anti-Rabbit IgG [HRP] Secondary Antibody at 1:100,000 dilution was used for 1 hour at room temperature.

Applications for TR alpha/NR1A1/Thyroid Hormone Receptor alpha Antibody (JE40-49)

Application
Recommended Usage

Western Blot

1:1000

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

1*TBS (pH7.4), 0.05% BSA and 40% Glycerol

Preservative

0.05% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TR alpha/NR1A1

Thyroid Hormone Receptor alpha is encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Long Name

Thyroid Hormone Receptor alpha

Alternate Names

NR1A1, THRA, v-ErbA1

Gene Symbol

THRA

Additional TR alpha/NR1A1 Products

Product Documents for TR alpha/NR1A1/Thyroid Hormone Receptor alpha Antibody (JE40-49)

Certificate of Analysis

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Product Specific Notices for TR alpha/NR1A1/Thyroid Hormone Receptor alpha Antibody (JE40-49)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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