TrkB Antibody (8D2E8) - BSA Free

Western Blot: TrkB Antibody (8D2E8) - BSA Free [NBP2-52523] -

ZEB 1 suppression by miRNAs maintains cancer stem cell properties. mRNA expression levels of cancer stem cell-related genes (A–D). (A) Cells transfected with ZEB1 inhibitor miRNAs upregulate TrkB mRNA expression apart from miR-101-3p, miR-139-5p, and miR-144-3p (t-test *, p = 0.02, *, p = 0.01, and **, p = 0.004, respectively). (B) miR-200c-3p does not affect ALDH mRNA expression compared to the other miRNAs, which increase its expression (Mann–Whitney **, p101 = 0.009, t-test **, p139 = 0.009, t-test ** p144 = 0.002, and t-test ***, p199 = 0.0006). (C) NANOG mRNA is significantly upregulated after transfection with miR-144-3p and miR-199b-5p and shows no significant upregulation for the other miRNAs (t-test **, p = 0.002, and *, p = 0.02, respectively). (D) HIF-1 alpha mRNA levels are upregulated after transfection with miR-144-3p but shows no statistical significance for the other microRNAs (t-test *, p = 0.03). (E) Western blot results of mRNA expression findings. Image collected and cropped by CiteAb from the following open publication (https://www.mdpi.com/1422-0067/24/6/5916), licensed under a CC-BY license. Not internally tested by Novus Biologicals.