7 results for "bromodomain-compounds&view=expanded" in Products

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(+)-JQ1

Catalog #: 4499
(2)
Citations (45)
Product Documents

Potent and selective BET bromodomain inhibitor; cell permeable

Chemical Name: (6S)-4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetic acid 1,1-dimethylethyl ester
Purity: ≥98%
Potent and selective BET bromodomain inhibitor; cell permeable

SGC-CBP30

Catalog #: 4889
(1)
Citations (13)
Product Documents

Potent CBP/p300 BRD inhibitor

Chemical Name: 2-[2-(3-Chloro-4-methoxyphenyl)ethyl]-5-(dimethyl-1,2-oxazol-4-yl)-1-[(2S)-2-(morpholin-4-yl)propyl]-1H-1,3-benzodiazole
Purity: ≥98%
Potent CBP/p300 BRD inhibitor

I-BET 762

Catalog #: 6521
Citations (1)
Product Documents

Potent and high affinity BET bromodomain inhibitor; anti-inflammatory; orally bioavailable.

Alternate Names: GSK525762A,Molibresib
Chemical Name: (4S)-6-(4-Chlorophenyl)-N-ethyl-8-methoxy-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine-4-acetamide
Purity: ≥98%
Potent and high affinity BET bromodomain inhibitor; anti-inflammatory; orally bioavailable.

CPI 203

Catalog #: 5331
(1)
Citations (3)
Product Documents

BET bromodomain inhibitor; arrests cell cycle at G1 phase

Alternate Names: TEN 010
Chemical Name: (6S)-4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetamide
Purity: ≥98%
BET bromodomain inhibitor; arrests cell cycle at G1 phase

(+)-JQ1 maleimide

Catalog #: 7576
Citations (1)
Product Documents

JQ1-maleimide functionalized probe; induces proteasomal degradation of BRD4

Chemical Name: (S)-N-(2-(2-(2-(2-(4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetamido)ethoxy)ethoxy)ethyl)-6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanamide
Purity: ≥95%
JQ1-maleimide functionalized probe; induces proteasomal degradation of BRD4

dTRIM 24

Catalog #: 6607
Citations (1)
Product Documents

TRIM24 Degrader (PROTAC®)

Chemical Name: (2S,4R)-1-((S)-15-(tert-Butyl)-1-(3-(N-(1,3-dimethyl-2-oxo-6-(3-propoxyphenoxy)-2,3-dihydro-1H-benzo[d]imidazol-5-yl)sulfamoyl)phenyl)-1,13-dioxo-5,8,11-trioxa-2,14-diazahexadecan-16-oyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
Purity: ≥98%
TRIM24 Degrader (PROTAC®)

JQ1-FITC

Catalog #: 7722
Citations (2)
Product Documents

Fluorescent BET bromodomain probe; suitable for use in TR-FRET

Chemical Name: (S)-5-(3-(1-(4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-2-oxo-7,10,13-trioxa-3-azahexadecan-16-yl)thioureido)-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid trifluoroacetate
Purity: ≥95%
Fluorescent BET bromodomain probe; suitable for use in TR-FRET
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