3 results for "cytokine-degraders&view=expanded" in Products

Potent MIF Degrader (PROTAC®)

Chemical Name: 8-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)-N-(4-(7-hydroxy-2-oxo-2H-benzo[e][1,3]oxazin-3(4H)-yl)phenyl)octanamide
Purity: ≥98%
Potent MIF Degrader (PROTAC®)
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Negative control for MD13 (Cat. No. 7503)

Chemical Name: N-(4-(7-Hydroxy-2-oxo-2H-benzo[e][1,3]oxazin-3(4H)-yl)phenyl)-8-((2-(1-methyl-2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)octanamide
Purity: ≥98%
Negative control for MD13 (Cat. No. 7503)
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Cereblon binder; induces ubiquitination and degradation of CK1α by E3 ubiquitin ligase

Chemical Name: 3-(4-Amino-1,3-dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione
Purity: ≥98%
Cereblon binder; induces ubiquitination and degradation of CK1α by E3 ubiquitin ligase
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