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173 results for "HMG-CoA Reductase/HMGCR" in Products
HMG-CoA Reductase/HMGCR Products
HMG-CoA reductase is the rate-limiting enzyme for cholesterol synthesis and is regulated via a negative feedback mechanism mediated by sterols and non-sterol metabolites derived from mevalonate, the product of the reaction catalyzed by reductase. Normally in mammalian cells this enzyme is suppressed by cholesterol derived from the internalization and degradation of low density lipoprotein (LDL) via the LDL receptor. Competitive inhibitors of the reductase induce the expression of LDL receptors ...
| Alternate Names: | Eptastatin sodium |
| Chemical Name: | (βR,δR,1S,2S,6S,8S,8aR)-1,2,6,7,8,8a-Hexahydro-β,δ,6-trihydroxy-2-methyl-8-[(2S)-2-methyl-1-oxobutoxy]-1-naphthaleneheptanoic acid monosodium salt |
| Purity: | ≥98% |
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| Chemical Name: | (±)-(3R*,5S*,6E)-7-[3-(4-Fluorophenyl)-1-(1-methyethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic acid sodium salt |
| Purity: | ≥98% |
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| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #JF0981 |
| Applications: | IHC, WB, Simple Western, IP |
![Western Blot: HMG-CoA Reductase/HMGCR Antibody (JF0981) [NBP2-66888]](https://resources.rndsystems.com/images/products/HMG-CoA-Reductase-HMGCR-Antibody-JF0981-Western-Blot-NBP2-66888-img0003.jpg "Western Blot: HMG-CoA Reductase/HMGCR Antibody (JF0981) [NBP2-66888]")
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| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #CL0259 |
| Applications: | IHC, WB, Mycoplasma |
![Western Blot: HMG-CoA Reductase/HMGCR Antibody (CL0259) [NBP2-61616]](https://resources.rndsystems.com/images/products/HMG-CoA-Reductase-HMGCR-Antibody-CL0259-Western-Blot-NBP2-61616-img0001.jpg "Western Blot: HMG-CoA Reductase/HMGCR Antibody (CL0259) [NBP2-61616]")
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| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #CL0260 |
| Applications: | IHC, WB, Mycoplasma |
![Immunohistochemistry-Paraffin: HMG-CoA Reductase/HMGCR Antibody (CL0260) [NBP2-61617]](https://resources.rndsystems.com/images/products/HMG-CoA-Reductase-HMGCR-Antibody-CL0260-Immunohistochemistry-Paraffin-NBP2-61617-img0010.jpg "Immunohistochemistry-Paraffin: HMG-CoA Reductase/HMGCR Antibody (CL0260) [NBP2-61617]")
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| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC |
![Immunohistochemistry-Paraffin: HMG-CoA Reductase/HMGCR Antibody [NBP1-91996]](https://resources.rndsystems.com/images/products/HMG-CoA-Reductase-HMGCR-Antibody-Immunohistochemistry-Paraffin-NBP1-91996-img0008.jpg "Immunohistochemistry-Paraffin: HMG-CoA Reductase/HMGCR Antibody [NBP1-91996]")
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| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #CL0259 |
| Applications: | IHC, WB |
![HMG-CoA Reductase/HMGCR Antibody (CL0259) Immunohistochemistry: HMG-CoA Reductase/HMGCR Antibody (CL0259) [NBP3-52097]](https://resources.rndsystems.com/images/products/nbp3-52097_mouse-hmg-coa-reductase-hmgcr-mab-cl0259-immunohistochemistry-27320261519624.jpg "Immunohistochemistry: HMG-CoA Reductase/HMGCR Antibody (CL0259) [NBP3-52097]")
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| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #CL0259 |
| Applications: | IHC, WB |
![HMG-CoA Reductase/HMGCR Antibody (CL0259) Immunohistochemistry-Paraffin: HMG-CoA Reductase/HMGCR Antibody (CL0260) [NBP3-52447]](https://resources.rndsystems.com/images/products/nbp3-52446_-immunohistochemistry-paraffin-639191183806877601.jpg "Immunohistochemistry-Paraffin: HMG-CoA Reductase/HMGCR Antibody (CL0260) [NBP3-52447]")
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| Chemical Name: | Cholest-5-ene-3β,25-diol |
| Purity: | ≥95% |
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| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #CL0259 |
| Applications: | IHC, WB |
![HMG-CoA Reductase/HMGCR Antibody (CL0259) - Azide and BSA Free Immunohistochemistry-Paraffin: HMG-CoA Reductase/HMGCR Antibody [NBP3-43943]](https://resources.rndsystems.com/images/products/nbp3-43943_mouse-hmg-coa-reductase-hmgcr-mab-cl0259-azide-bsa-free-282202512195421.jpg "Immunohistochemistry-Paraffin: HMG-CoA Reductase/HMGCR Antibody [NBP3-43943]")
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| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #CL0260 |
| Applications: | IHC, WB |
![HMG-CoA Reductase/HMGCR Antibody (CL0260) Immunohistochemistry: HMG-CoA Reductase/HMGCR Antibody (CL0260) [NBP3-52096]](https://resources.rndsystems.com/images/products/nbp3-52096_mouse-hmg-coa-reductase-hmgcr-mab-cl0260-immunohistochemistry-27320261526915.jpg "Immunohistochemistry: HMG-CoA Reductase/HMGCR Antibody (CL0260) [NBP3-52096]")
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| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #CL0260 |
| Applications: | IHC, WB |
![HMG-CoA Reductase/HMGCR Antibody (CL0260) Immunohistochemistry-Paraffin: SATB2 Antibody (CL0320) [NBP3-52448]](https://resources.rndsystems.com/images/products/nbp3-52447_-immunohistochemistry-paraffin-639191183811501126.jpg "Immunohistochemistry-Paraffin: SATB2 Antibody (CL0320) [NBP3-52448]")
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| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #6Y9L8 |
| Applications: | WB |
![Western Blot: HMG-CoA Reductase/HMGCR Antibody (6Y9L8) [NBP3-15641]](https://resources.rndsystems.com/images/products/HMG-CoA-Reductase-HMGCR-Antibody-6Y9L8-Western-Blot-NBP3-15641-img0001.jpg "Western Blot: HMG-CoA Reductase/HMGCR Antibody (6Y9L8) [NBP3-15641]")
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| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #CL0260 |
| Applications: | IHC, WB |
![HMG-CoA Reductase/HMGCR Antibody (CL0260) - Azide and BSA Free Immunohistochemistry-Paraffin: HMG-CoA Reductase/HMGCR Antibody [NBP3-43933]](https://resources.rndsystems.com/images/products/nbp3-43933_mouse-hmg-coa-reductase-hmgcr-mab-cl0260-azide-bsa-free-282202512135869.jpg "Immunohistochemistry-Paraffin: HMG-CoA Reductase/HMGCR Antibody [NBP3-43933]")
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| Alternate Names: | Mevinolin |
| Chemical Name: | (2S)-(1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-Hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl-2-methyl butanoate |
| Purity: | ≥97% |
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| Chemical Name: | (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-Hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyly-2,2-dimethyl butanoate |
| Purity: | ≥98% |
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| Reactivity: | Human |
| Source: | E. coli |
| Accession #: | P04035 |
| Applications: | Enzyme Activity |
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| Alternate Names: | NK-104 |
| Chemical Name: | (3R,5S,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoic acid hemicalcium salt |
| Purity: | ≥98% |
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| Chemical Name: | (3R,5S,6E)-7-[4-(4-Fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl])-3,5-dihydroxyhept-6-enoic acid hemicalcium salt |
| Purity: | ≥98% |
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| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | ELISA, Flow, ICC/IF |
![Immunocytochemistry/ Immunofluorescence: HMG-CoA Reductase/HMGCR Antibody [NBP3-05292]](https://resources.rndsystems.com/images/products/HMG-CoA-Reductase-HMGCR-Antibody-Immunocytochemistry-Immunofluorescence-NBP3-05292-img0001.jpg "Immunocytochemistry/ Immunofluorescence: HMG-CoA Reductase/HMGCR Antibody [NBP3-05292]")
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| Reactivity: | Human |
| Sensitivity: | 0.38 ng/mL |
| Assay Range: | 0.63 - 40 ng/mL |
| Applications: | ELISA |
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| Reactivity: | Human |
| Applications: | WB |
![Other: HMG-CoA Reductase/HMGCR 293T Cell Transient Overexpression Lysate [H00003156-T01]](https://resources.rndsystems.com/images/products/qc_test-H00003156-T01-1.jpg "Other: HMG-CoA Reductase/HMGCR 293T Cell Transient Overexpression Lysate [H00003156-T01]")
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| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
![Western Blot: HMG-CoA Reductase/HMGCR AntibodyBSA Free [NBP3-03778]](https://resources.rndsystems.com/images/products/HMG-CoA-Reductase-HMGCR-Antibody-Western-Blot-NBP3-03778-img0002.jpg "Western Blot: HMG-CoA Reductase/HMGCR AntibodyBSA Free [NBP3-03778]")
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| Reactivity: | Mouse |
| Sensitivity: | 0.31 ng/mL (example only; lot dependent) |
| Assay Range: | 0.781 - 50 ng/mL (example only; lot dependent) |
| Applications: | ELISA |
![Mouse HMG-CoA Reductase/HMGCR ELISA Kit (Colorimetric) ELISA: Mouse HMG-CoA Reductase/HMGCR ELISA Kit (Colorimetric) [NBP3-54138]](https://resources.rndsystems.com/images/products/elisa/nbp3-54138_-elisa-639197509438706693.png "ELISA: Mouse HMG-CoA Reductase/HMGCR ELISA Kit (Colorimetric) [NBP3-54138]")
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| Reactivity: | Rat |
| Sensitivity: | 0.134 ng/mL (example only; lot dependent) |
| Assay Range: | 0.312 - 20 ng/mL (example only; lot dependent) |
| Applications: | ELISA |
![Rat HMG-CoA Reductase/HMGCR ELISA Kit (Colorimetric) ELISA: Rat HMG-CoA Reductase/HMGCR ELISA Kit (Colorimetric) [NBP3-54139]](https://resources.rndsystems.com/images/products/elisa/nbp3-54139_-elisa-639197506910645003.png "ELISA: Rat HMG-CoA Reductase/HMGCR ELISA Kit (Colorimetric) [NBP3-54139]")
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