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28 results for "inflammasomes-peptides&view=expanded" in Products

Cell-permeable, irreversible caspase inhibitor

Chemical Name: Benzyloxycarbonyl-Val-Ala-Asp(OMe)-fluoromethylketone
Purity: ≥95%
Cell-permeable, irreversible caspase inhibitor
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GSDMD (Gasdermin D) agonist, activator of pyroptosis, also GLP-1R agonist

Chemical Name: 6,7-Dichloro-N-(1,1-dimethylethyl)-3-(methylsulfonyl)-2-quinoxalinamine
Purity: ≥98%
GSDMD (Gasdermin D) agonist, activator of pyroptosis, also GLP-1R agonist
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Potent NLRP3 inflammasome inhibitor; inhibits IL-1β production

Alternate Names: CP-456773,MCC 950
Chemical Name: N-[[(1,2,3,5,6,7-Hexahydro-s-indacen-4-yl)amino]carbonyl]-4-(1-hydroxy-1-methylethyl)-2-furansulfonamide sodium salt
Purity: ≥98%
Potent NLRP3 inflammasome inhibitor; inhibits IL-1β production
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Potent DPP IV inhibitor; activates NLRP1b inflammasome

Alternate Names: Val-boroPro,BXCL 701
Chemical Name: B-[(2R)-1-[(2S)-2-Amino-3-methyl-1-oxobutyl]-2-pyrrolidinyl]boronic acid methanesulfonate
Purity: ≥98%
Potent DPP IV inhibitor; activates NLRP1b inflammasome
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Caspase-1 and NLRP3 inflammasome inhibitor

Chemical Name: Ethyl 2[(2-chlorophenyl)(hydroxy)methyl]acrylate
Purity: ≥98%
Caspase-1 and NLRP3 inflammasome inhibitor
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NLRP3 inhibitor; active in vivo

Chemical Name: 4-[[4-Oxo-2-thioxo-3-[[3-(trifluoromethyl)phenyl]methyl]-5-thiazolidinylidene]methyl]benzoic acid
Purity: ≥98%
NLRP3 inhibitor; active in vivo
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NLRP3 inflammasome inhibitor

Alternate Names: JC121
Chemical Name: N-[2-[4-(Aminosulfonyl)phenyl]ethyl]-5-chloro-2-methoxybenzamide
Purity: ≥98%
NLRP3 inflammasome inhibitor
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NLRP3 inflammasome inhibitor; disrupts inflammasome formation

Chemical Name: 3-(Methylsulfonyl)propanenitrile
Purity: ≥98%
NLRP3 inflammasome inhibitor; disrupts inflammasome formation
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Potent NLRP3 inflammasome inhibitor

Chemical Name: 2-((1,2,3,5,6,7-Hexahydro-s-indacen-4-yl)amino)-5-(pyridin-2-ylmethyl)-[1,2,4]triazolo[1,5-a]pyrimidine-7(4H)-thione
Purity: ≥95%
Potent NLRP3 inflammasome inhibitor
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Potent brain penetrant NLRP3 inflammasome inhibitor

Chemical Name: 2-[6-[[(3R)-1-Ethyl-3-piperidinyl]amino]-3-pyridazinyl]-3-methyl-5-(trifluoromethyl)phenol
Purity: ≥98%
Potent brain penetrant inhibitor of the NLRP3 inflammasome
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