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119 results for "Jak1" in Products
Jak1 Products
Jak1, Jak 2, and Jak3 belong to the Janus Kinases family of protein tyrosine kinases that couple to cytokine receptors once activated by their corresponding ligands. Activation of Jak family members occurs via phosphorylation at two adjacent tyrosine residues as well as potentially one or more serine residues. Jaks activate members of the STAT family of transcription factors by phosphorylating critical tyrosine regulatory sites.
Jak1 is required for the activation of STAT1 and STAT2 in ...
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG2A Monoclonal Clone #452804 |
| Applications: | WB, Simple Western |
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| Reactivity: | Human, Mouse, Rat |
| Details: | Rat IgG2B Monoclonal Clone #413104 |
| Applications: | WB, Simple Western |
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| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #JM75-03 |
| Applications: | IHC, WB, Flow |
![Western Blot: Jak1 Antibody (JM75-03) [NBP2-75547]](https://resources.rndsystems.com/images/products/Jak1-Antibody-JM75-03-Western-Blot-NBP2-75547-img0005.jpg "Western Blot: Jak1 Antibody (JM75-03) [NBP2-75547]")
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| Alternate Names: | Tofacitinib citrate |
| Chemical Name: | (3R,4R)-4-Methyl-3-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-β-oxo-1-piperidinepropanenitrile citrate |
| Purity: | ≥98% |
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| Reactivity: | Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ICC/IF |
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| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB |
![Jak1 [p Tyr1022] Antibody](https://resources.rndsystems.com/images/products/nb100-82005_rabbit-polyclonal-jak1-p-tyr1022-antibody-113202594526.jpg "Immunohistochemistry-Paraffin: Jak1 [p Tyr1022] Antibody [NB100-82005] -")
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| Alternate Names: | INCB018424 |
| Chemical Name: | (3R)-3-Cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]propanenitrile |
| Purity: | ≥98% |
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| Reactivity: | Human |
| Source: | HEK293 |
| Accession #: | P23458.2 |
| Applications: | Bioactivity |
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| Alternate Names: | INCB 28050 |
| Chemical Name: | 1-(Ethylsulfonyl)-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]-3-azetidineacetonitrile |
| Purity: | ≥98% |
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| Chemical Name: | (3S,4R)-3-Ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)-1-pyrrolidinecarboxamide |
| Purity: | ≥98% |
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| Reactivity: | Human |
| Sensitivity: | 0.094 ng/mL |
| Assay Range: | 0.156-10 ng/mL |
| Applications: | ELISA |
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| Reactivity: | Human |
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| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ICC/IF |
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| Alternate Names: | JAK inhibitor I |
| Chemical Name: | 2-(1,1-Dimethylethyl)-9-fluoro-1,6-dihydro-7H-benz[h]imidazo[4,5-f]isoquinolin-7-one |
| Purity: | ≥98% |
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| Chemical Name: | (3R)-3-Cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]propanenitrile phosphate |
| Purity: | ≥98% |
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| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #SR1138 |
| Applications: | IHC, WB |
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| Reactivity: | Human |
| Source: | Wheat germ |
| Applications: | WB, ELISA, AP, MA |
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| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #7Q1B2 |
| Applications: | WB, ELISA |
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| Reactivity: | Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ICC/IF |
![Jak1 Antibody [Alexa Fluor® 488]](https://resources.rndsystems.com/images/icons/RnD-Default-Product-Image_Antibodies-Icon.svg "Jak1 Antibody [Alexa Fluor® 488]"){kind=icon}
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| Reactivity: | Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ICC/IF |
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| Reactivity: | Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ICC/IF |
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| Reactivity: | Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ICC/IF |
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| Reactivity: | Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ICC/IF |
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| Reactivity: | Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ICC/IF |
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| Reactivity: | Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ICC/IF |
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