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VGLUT1/SLC17A7 Small Molecules and Peptides

Vesicular Glutamate Transporter 1 (VGLUT1), also known as SLC17A7, is an integral membrane protein involved in glutamate uptake into synaptic vesicles. Human VGLUT1/SLC17A7 is a 560 amino acid (aa) 12-transmembrance protein with a predicted molecular weight of approximately 61 kDa. It shares 98% aa sequence identity with the mouse and rat orthologs. VGLUT1/SLC17A7 is expressed in pre-synaptic vesicles and mediates the accumulation of neurotransmitter (glutamate) into synaptic vesicles. It is an ...

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Risdiplam

Catalog #: 7916
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Selective SMN2 gene splicing modifier

Chemical Name: 7-(4,7-Diazaspiro[2.5]oct-7-yl)-2-(2,8-dimethylimidazo[1,2-b]pyridazin-6-yl)-4H-pyrido[1,2-a]pyrimidin-4-one
Purity: ≥98%
Selective SMN2 gene splicing modifier
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