TGF beta 1/2/3 Antibody (1D11R) [mFluor Violet 610 SE]

Name: TGF beta 1/2/3 Antibody (1D11R) [mFluor Violet 610 SE]
Brand: Novus Biologicals
SKU: FAB1835RMFV610
Price: 639 USD
Availability: InStock

Novus Biologicals | Catalog # FAB1835RMFV610

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Product Documents

Recombinant Monoclonal Antibody

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Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species Reactivity

Multi-Species

Applications

Neutralization

Label

mFluor Violet 610 SE (Excitation = 421 nm, Emission = 613 nm)

Antibody Source

Recombinant Monoclonal Mouse IgG₁ Clone # 1D11R

View all TGF-beta 1, 2, 3 Primary Antibodies »

Product Specifications

Immunogen

Bovine bone-derived TGF-beta 1 and TGF-beta 2

Specificity

Detects bovine, chicken, mouse, and human TGF-beta in ELISAs and Western blots. It recognizes human TGF-beta 1, TGF-beta 2, and TGF-beta 3.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG₁

Description

This conjugate is made on demand and is not held in inventory. Each order represents a unique lot. All conjugates are generated using validated conjugation protocols and meet strict degree of labeling (F/P) specifications; additional information is available upon request. The antibody concentration is provided on the individual product label.

For specialized conjugation needs, like large quantities, specific concentrations, and defined F/P ratios, bulk and custom antibody conjugation services are available.

Applications for TGF beta 1/2/3 Antibody (1D11R) [mFluor Violet 610 SE]

Application

Recommended Usage

Neutralization

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Recommended applications are based on validated applications from the unconjugated base product MAB1835R. This conjugated antibody is not kept in inventory and is made to order using validated conjugation protocols.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from cell culture supernatant

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: TGF-beta 1, 2, 3

TGF-beta 1, -2 and -3 are highly pleiotropic cytokines that act as cellular switches to regulate immune function, proliferation and epithelial-mesenchymal transition.TGF-beta associates with LAP after secretion, and this complex is covalently linked to one of three latent TGF-beta binding proteins (LTBPs). TGF-beta is activated from latency by Plasmin, matrix metalloproteases, Thrombospondin 1, or a subset of integrins. TGF-beta signals through a complex of TGF-beta RII and either TGF-beta RI/ALK-5 or ALK-1. TGF-beta induced signaling is modulated by the accessory proteins Betaglycan/TGF-beta RIII and Endoglin.

Long Name

Transforming Growth Factor beta 1, 2, and 3

Alternate Names

CED, DPD1, LAP, TGFB, TGFB1, TGFbeta, transforming growth factor, beta 1

Additional TGF-beta 1, 2, 3 Products

Product Documents for TGF beta 1/2/3 Antibody (1D11R) [mFluor Violet 610 SE]

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Certificate of Analysis

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Product Specific Notices for TGF beta 1/2/3 Antibody (1D11R) [mFluor Violet 610 SE]

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.