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17 results for "additional-stem-cell-dedifferentiation-products&view=expanded" in Products

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CHIR 99021

Catalog #: 4423
(19)
Citations (2073)
Product Documents

Highly selective GSK-3 inhibitor; acts as Wnt activator

GMP Version Available: TB4423-GMP
GMP
Alternate Names: CHIR99021,CT99021
Chemical Name: 6-[[2-[[4-(2,4-Dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]amino]-3-pyridinecarbonitrile
Purity: ≥98%
Cardiomyocyte derived from human induced pluripotent stem cells (hiPSCs) using CHIR 99021.
(2)

CHIR 99021 GMP

Catalog #: TB4423-GMP
Citations (4)
Product Documents

CHIR 99021 synthesized to cGMP guidelines

Chemical Name: 6-[[2-[[4-(2,4-Dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]amino]-3-pyridinecarbonitrile
Purity: ≥99%
CHIR 99021 synthesized to cGMP guidelines
(2)

O4I2

Catalog #: 5664
Product Documents

Oct3/4 inducer; induces expression of pluripotent-associated genes

Chemical Name: Ethyl 2-[(4-chlorophenyl)amino]-4-thiazolecarboxylate
Purity: ≥98%
Oct3/4 inducer; induces expression of pluripotent-associated genes

Valproic acid, sodium salt

Catalog #: 2815
(2)
Citations (26)
Product Documents

Histone deacetylase inhibitor

Alternate Names: VPA,Sodium Valproate
Chemical Name: Sodium 2-propylpentanoate
Histone deacetylase inhibitor

PD 0325901

Catalog #: 4192
(8)
Citations (382)
Product Documents

Potent inhibitor of MEK1/2

Alternate Names: PD325901
Chemical Name: N-[(2R)-2,3-Dihydroxypropoxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide
Purity: ≥99%
Potent inhibitor of MEK1/2

RepSox

Catalog #: 3742
(1)
Citations (38)
Product Documents

Potent and selective inhibitor of TGF-βRI

Alternate Names: E-616452,SJN 2511,ALK5 Inhibitor II
Chemical Name: 2-[3-(6-Methylpyridin-2-yl)-1H-pyrazol-4-yl]-1,5-naphthyridine
Purity: ≥99%
Potent and selective inhibitor of TGF-βRI

Tranylcypromine hydrochloride

Catalog #: 3852
(2)
Citations (16)
Product Documents

Irreversible inhibitor of LSD1; also inhibits MAO

Alternate Names: 2-PCPA
Chemical Name: (±)-trans-2-Phenylcyclopropylamine hydrochloride
Purity: ≥98%
Irreversible inhibitor of LSD1; also inhibits MAO

Trichostatin A

Catalog #: 1406
(1)
Citations (66)
Product Documents

Potent histone deacetylase inhibitor

Chemical Name: (2E,4E,6R)-7-(4-(Dimethylamino)phenyl)-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide
Purity: ≥95%
Potent histone deacetylase inhibitor

5-Azacytidine

Catalog #: 3842
Citations (14)
Product Documents

DNA methyltransferase inhibitor

Chemical Name: 4-Amino-1-β-D-ribofuranosyl-1,3,5-triazin-2(1H)-one
Purity: ≥98%
DNA methyltransferase inhibitor

Kenpaullone

Catalog #: 1398
Citations (30)
Product Documents

GSK-3β inhibitor; also inhibits cdks

Chemical Name: 9-Bromo-7,12-dihydro-indolo[3,2-d][1]benzazepin-6(5H)-one
Purity: ≥98%
GSK-3β inhibitor; also inhibits cdks
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