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29 results for "other-differentiation-compounds&view=expanded" in Products

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SB 431542

Catalog #: 1614
(13)
Citations (2376)
Product Documents

Potent, selective inhibitor of TGF-βRI, ALK4 and ALK7

GMP Version Available: TB1614-GMP
GMP
Chemical Name: 4-[4-(1,3-benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]benzamide
Purity: ≥99%
dopaminergic neurons derived from hiPSCs using SB 431542
(2)

LDN 193189 dihydrochloride

Catalog #: 6053
(3)
Citations (153)
Product Documents

Potent and selective ALK2 and ALK3 inhibitor; inhibits BMP4 signaling; promotes neural induction of hPSCs

GMP Version Available: TB6053-GMP
GMP
Alternate Names: LDN 193189 2HCl
Chemical Name: 4-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline dihydrochloride
Purity: ≥98%
Application of LDN 193189 in motor neurons differentiated from iPSCs
(2)

Dorsomorphin dihydrochloride

Catalog #: 3093
(3)
Citations (314)
Product Documents

Potent AMPK inhibitor; also BMP type I receptor inhibitor

Alternate Names: Compound C,BML-275
Chemical Name: 6-[4-[2-(1-Piperidinyl)ethoxy]phenyl]-3-(4-pyridinyl)-pyrazolo[1,5-a]pyrimidine dihydrochloride
Purity: ≥98%
Potent AMPK inhibitor; also BMP type I receptor inhibitor

A 83-01

Catalog #: 2939
(12)
Citations (1077)
Product Documents

Selective inhibitor of TGF-βRI, ALK4 and ALK7

Chemical Name: 3-(6-Methyl-2-pyridinyl)-N-phenyl-4-(4-quinolinyl)-1H-pyrazole-1-carbothioamide
Purity: ≥98%
Adult Stem Cell-derived Liver Organoids
(6)

HG-9-91-01

Catalog #: 8985
Product Documents

Potent pan-salt inducible kinases (SIK1, SIK2 and SIK3) inhibitor. Also inhibits Lat-B-induced EP differentiation via nuclear YAP1 accumulation.

Alternate Names: SIK inhibitor 1
Chemical Name: 1-(2,4-Dimethoxyphenyl)-3-(2,6-dimethylphenyl)-1-(6-((4-(4-methylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)urea
Purity: ≥98%
Potent pan-salt inducible kinases (SIK1, SIK2 and SIK3) inhibitor. Also inhibits Lat-B-induced EP differentiation via nuclear YAP1 accumulation.

T3

Catalog #: 6666
Citations (9)
Product Documents

Thyroid hormone; also promotes differentiation of oligodendroglial precursor cells

Chemical Name: O-(4-Hydroxy-3-iodophenyl-3,5-diiodo-L-tyrosine
Purity: ≥98%
Thyroid hormone; also promotes differentiation of oligodendroglial precursor cells

DMH-1

Catalog #: 4126
(4)
Citations (313)
Product Documents

Selective ALK2 inhibitor

Chemical Name: 4-[6-[4-(1-Methylethoxy)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]-quinoline
Purity: ≥98%
Selective ALK2 inhibitor

AS 1842856

Catalog #: 4265
Citations (6)
Product Documents

Potent and selective Foxo1 inhibitor; orally bioavailable

Chemical Name: 5-Amino-7-(cyclohexylamino)-1-ethyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid
Purity: ≥98%
Potent and selective Foxo1 inhibitor; orally bioavailable

SIS3

Catalog #: 5291
Citations (37)
Product Documents

Selective Smad3 inhibitor; inhibits TGF-βR1 signaling

Chemical Name: 1,2,3,4-Tetrahydro-6,7-dimethoxy-2-[(2E)-3-(1-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-1-oxo-2-propenyl]-isoquinoline hydrochloride
Purity: ≥97%
Selective Smad3 inhibitor; inhibits TGF-βR1 signaling

TPPB

Catalog #: 5343
Citations (32)
Product Documents

High affinity PKC activator; also APP modulator

Chemical Name: (2E,4E)-N-[(2S,5S)-1,2,3,4,5,6-Hexahydro-5-(hydroxymethyl)-1-methyl-2-(1-methylethyl)-3-oxo-1,4-benzodiazocin-8-yl]-5-[4-(trifluoromethyl)phenyl]-2,4-pentadienamide
Purity: ≥98%
High affinity PKC activator; also APP modulator
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