GMP

LDN 193189

Tocris Bioscience | Catalog # TB6053-GMP

LDN 193189 synthesized to cGMP guidelines
Tocris Bioscience

Key Product Details

Description

LDN 193189 synthesized to cGMP guidelines
View all BMP and Other Activin Receptor Activators »

Product Description

LDN 193189 synthesized to cGMP guidelines. Suitable for use as an ancillary reagent in the further manufacturing of cell therapies.

Research use only LDN 193189 also available.

For more information about how LDN 193189 dihydrochloride may be used, see our protocols: Generation of β cells from hPSCs, Generating Midbrain Dopaminergic Neurons from hPSCs, Accelerated Induction of Cortical Neurons from hiPSCs.

Licensing Information

Sold for research purposes only under exclusive agreement from The Brigham and Women's Hospital Inc. US patents 8,507,501 and 9,045,484. A license may be required for use in stem cell-based therapies. Please contact Technical Support for further details: techsupport@bio-techne.com.

Current Good Manufacturing Practice (cGMP) is a harmonized set of guidelines that when implemented will ensure safe, reliable, consistent and quality-assured products. The Tocris range of cGMP small molecules is manufactured following relevant sections of ICH Q7 guidelines. Our highly skilled team has full control over the cGMP process, meaning we can ensure: a quality-assured manufacturing system, batch-to-batch consistency, consistent supply, traceability from starting material to final product, and animal-free production. Find out more about the Tocris range of cGMP compounds.

Product Specifications for LDN 193189

Molecular Weight

479.40

Formula

C25H22N6.2HCl

Storage

Store at -20°C (± 5°C)

Purity

≥99%

Chemical Name

4-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline dihydrochloride

CAS Number

1435934-00-1

InChI Key

CMQXLLAILGGLRV-UHFFFAOYSA-N

SMILES

N1(C2=CC=C(C3=CN4N=CC(C5=CC=NC6=C5C=CC=C6)=C4N=C3)C=C2)CCNCC1.Cl.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Calculators

Calculate the mass, volume, or concentration required for a solution.

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Calculate the dilution required to prepare a stock solution.

x
=
x

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Background References

References are publications that support the biological activity of the product.

There are currently no references for this product.

Product Documents for LDN 193189

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for LDN 193189

For preclinical, or clinical ex vivo use

Customer Reviews for LDN 193189

There are currently no reviews for this product. Be the first to review LDN 193189 and earn rewards!

Have you used LDN 193189?

Submit a review and receive an Amazon gift card!

$25/€18/£15/$25CAN/¥2500 Yen for a review with an image

$10/€7/£6/$10CAN/¥1110 Yen for a review without an image

Submit a review
Amazon Gift Card