Cadherin-12: Products

The cadherin superfamily is a large family of membrane-associated glycoproteins that engage in calcium-dependent cell-cell adhesion events. Cadherin-12, also known as Brain‑Cadherin and N-Cadherin 2, is a 150 kDa classical cadherin. Classical family molecules are modular in their extracellular region, mediating cell adhesion through their five EC calcium-binding repeats.

Cadherin-12 is expressed specifically in CNS neurons. The bulk of its expression is postnatal, and it is proposed to be involved in synaptogenesis. As a classic cadherin, Cadherin-12 will form homodimers and promote intercellular adhesion with itself and, possibly, Cadherins-8 and -14.

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Novus Biologicals provides the life science community with high-performing antibodies to over 20,000 unique targets. These antibodies are available conjugated to multiple fluorophores and tested in numerous assays and species. read more
ProteinSimple develops and manufactures proprietary, fully automated systems for protein analysis. read more
- Simple Plex Assays