(2R,3S)-Chlorpheg
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Description: Weak NMDA antagonist
Chemical Name: (2R,3S)-β-p-Chlorophenylglutamic acid
Biological Activity
(2R,3S)-Chlorpheg is a weakly active NMDA receptor antagonist.Technical Data
M.Wt:
257.67
Formula:
C11H12ClNO4
Solubility:
Soluble to 75 mM in 1eq. NaOH with gentle warming
Storage:
Store at RT
CAS No:
140924-23-8
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
-
Differential actions of 3-(4-chlorophenyl)glutamic acid stereoisomers and L-trans-pyrrolidine-2,4-dicarboxylic acid upon L-homocysteic acid and L-glutamic acid-induced responses from rat spinal motoneurones.
Chalmers et al.
Neuropharmacology, 1995;34:1589 -
Diastereoselective synthesis of all four isomers of 3-(4-chlorophenylglutamic acid: identification of the isomers responsible for the potentiation of L-homocysteic acid-evoked depolarizations in neonatal rat motoneurons.
Jane et al.
J.Med.Chem., 1996;39:4738
Product Datasheets
Certificate of Analysis is currently unavailable on-line. Please contact Customer Service
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