ACBC
Chemical Name: 1-Aminocyclobutane-1-carboxylic acid
Biological Activity
ACBC is a NMDA receptor partial agonist, acting at the glycine site of GluN1 (formally NR1).Please refer to IUPHAR Guide to Pharmacology for the most recent naming conventions.
Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Mechanism of partial agonist action at the NR1 subunit of NMDA receptors.
Inanobe et al.
Neuron, 2005;47:71 -
1-Aminocyclobutane-1-carboxylic acid (ACBC): a specific antagonist of the NMDA receptor coupled glycine receptor.
Hood et al.
Eur.J.Pharmacol., 1989;161:281 -
Neuropharmacological characterization of 1-aminocyclopropane-1-carboxylate and 1-aminocyclobutane-1-carboxylate, ligands of the N-MthD.-aspartate-associated glycine receptor.
Rao et al.
Neuropharmacology, 1990;29:305
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