AG 494

Biological Activity

Technical Data

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

1. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death.
   Fox JT, Sakamuru S, Huang R
   Proc. Natl. Acad. Sci. U.S.A., 2012;109(14):5423-8.
2. Tyrphostins that suppress the growth of human papilloma virus 16-immortalized human keratinocytes.
   Ben-Bassat et al.
   J.Pharmacol.Exp.Ther., 1999;290:1442
3. Tyrphostins. 2. Heterocyclic and α-substituted benzylidenemalononitrile tyrophostins as potent inhibitors of EGF receptor and ErbB2/neu tyrosine kinases.
   Gazit et al.
   J.Med.Chem., 1991;34:1896
4. Cross-talk between the calcium-sensing receptor and the epidermal growth factor receptor in Rat-1 fibroblasts.
   Tomlins et al.
   Exp.Cell Res., 2005;308:439

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