[Ala11,22,28]VIP
Description: Potent, highly selective VPAC1 agonist
Biological Activity
Potent and highly selective agonist for the human VPAC1 receptor (Ki values are 7.4 and 2352 nM for binding to human recombinant VPAC1 and VPAC2 receptors respectively).Technical Data
M.Wt:
3160.68
Formula:
C139H231N43O39S
Sequence:
HSDAVFTDNYARLRKQMAVKKALNSILA-NH2
Storage:
Desiccate at -20°C
CAS No:
291524-04-4
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
-
Identification of key residues for interaction of vasoactive intestinal peptide with human VPAC1 and VPAC2 receptors and development of a highly selective VPAC1 agonist.
Nicole et al.
J.Biol.Chem., 2000;275:24003
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