Home / Lipoxygenase Inhibitors / BW-B 70C

BW-B 70C

Catalog #: 1304
1 Citation Datasheet / COA / SDS

Discontinued Product

1304 has been discontinued.
View all Lipoxygenase Inhibitors products.
BW-B 70C | CAS No. 134470-38-5 | Lipoxygenase Inhibitors
1 Image
Description: 5-Lipoxygenase inhibitor

Chemical Name: N-[3-[3-(-Fluorophenoxy)phenyl]-1-methyl-2-propenyl]-N-hydroxyurea

Purity: ≥98%

Product Details
Citations (1)
Reviews
Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

BW-B 70C is a potent and selective inhibitor of 5-lipoxygenase. Long half-life and high oral bioavailability in vivo.

Technical Data

M.Wt:
316.33
Formula:
C17H17FN2O3
Solubility:
Soluble to 3 mM in ethanol and to 3 mM in DMSO
Purity:
≥98%
Storage:
Desiccate at -20°C
CAS No:
134470-38-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death.
    Fox JT, Sakamuru S, Huang R
    Proc. Natl. Acad. Sci. U.S.A., 2012;109(14):5423-8.
  2. A cell cycle role for the epigenetic factor CTCF-L/BORIS.
    Rosa-Garrido M, Ceballos L, Alonso-Lecue P, Abraira C, Delgado MD, Gandarillas A
    PLoS ONE, 2012;7(6):e39371.
  3. Anti-Inflammatory Effects of OxPAPC Involve Endothelial Cell-Mediated Generation of LXA4.
    Yunbo Ke, Noureddine Zebda, Olga Oskolkova, Taras Afonyushk, Evgeny Berdyshev, Yufeng Tian, Fanyong Meng, Nicolene Sarich, Valery N Bochkov, Ji Ming Wang, Anna A Birukova, Konstantin G Birukov
    Circulation Research, 2017;0(0):1524-4571.

Product Datasheets

COA view current batch
Or select another batch:
View Batch
SDS
Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Citation for BW-B 70C

The citations listed below are publications that use Tocris products. Selected citations for BW-B 70C include:

1 Citation: Showing 1 - 1

  1. Plasticity of cytochrome P450 isozyme expression in rat trigeminal ganglia neurons during inflammation.
    Authors: Ruparel Et al.
    J Cell Biol  2012;153:2031

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for BW-B 70C

There are currently no reviews for this product. Be the first to review BW-B 70C and earn rewards!

Have you used BW-B 70C?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.