CRF (6-33)

Name: CRF (6-33)
Brand: Tocris Bioscience
SKU: 1607
Price: 405 USD

Catalog #: 1607 Datasheet / COA / SDS

Discontinued Product

1607 has been discontinued.

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Description: CRF-binding protein inhibitor

Alternative Names: Corticotropin-Releasing Factor (6-33)

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Product Details

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Biological Activity Technical Data Additional Information Background Product Datasheets Calculators

Biological Activity

CRF (6-33) is a corticotropin-releasing factor binding protein (CRFBP) inhibitor peptide; displaces CRF from CRFBP. Suppresses body weight gain and increases motor activity in obese rats in vivo.

Technical Data

M.Wt:

3220.68

Formula:

C₁₄₁H₂₃₁N₄₁O₄₃S

Sequence:

ISLDLTFHLLREVLEMARAEQLAQQAHS

Solubility:

Soluble to 1 mg/ml in water

Storage:

Desiccate at -20°C

CAS No:

120066-38-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:

Sold with the permission of the SALK Institute

Background References

Dissociation of arousal-like from anxiogenic-like actions of brain corticotropin-releasing factor receptor ligands in rats.
Heinrichs et al.
Behav.Brain Res., 2001;122:43
Selective stimulatory actions of corticotropin-releasing factor ligands on correlates of energy balance.
Heinrichs et al.
Physiol.Behav., 2001;74:5
The binding protein of corticotropin-releasing factor: ligand-binding site and subunit structure.
Jahn et al.
Proc.Natl.Acad.Sci.U.S.A., 2002;99:12055

Product Datasheets

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

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