Deltorphin I
Biological Activity
Deltorphin I is a potent δ-opioid receptor agonist (IC50 = 0.5 nM in human granulocytes). Exhibits a high rate of blood-brain barrier penetrance.Technical Data
(Modifications: Ala-2 = D-Ala, Gly-7 = C-terminal amide)
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Deltorphin transport across the blood-brain barrier.
Fiori et al.
Proc.Natl.Acad.Sci.USA, 1997;94:9469 -
[D-Ala2]Deltorphin I binding and pharmacological evidence for a special subtype of δ opioid receptor on human and invertebrate immune cells.
Stefano et al.
Proc.Natl.Acad.Sci.USA, 1992;89:9316 -
Deltorphins: a family of naturally occurring peptides with high affinity and selectivity for δ opioid binding sites.
Erspamer et al.
Proc.Natl.Acad.Sci.USA, 1989;86:5188
Product Datasheets
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Citation for Deltorphin I
The citations listed below are publications that use Tocris products. Selected citations for Deltorphin I include:
1 Citation: Showing 1 - 1
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Spinal activation of delta opioid receptors alleviates cancer-related bone pain.
Authors: Otis Et al.
Neuroscience 2011;183:221
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