HNGF6A
Discontinued Product
Biological Activity
HNGF6A is a humanin analog; increases glucose stimulated insulin secretion and glucose metabolism in vivo and in vitro. Also enhances glucose sensing in βTC3 cells and lowers blood glucose in Zucker diabetic fatty rats. Prevents endothelial dysfunction and delays progression of atherosclerosis in vivo. Protects neurons from NMDA-induced toxicity.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Humanin Preserves Endothelial Function and Prevents Atherosclerotic Plaque Progression in Hypercholesterolemic ApoE Deficient Mice.
Oh YK, Bachar AR, Zacharias DG et al.
Atherosclerosis;219(1):65-73. -
Humanin: a novel central regulator of peripheral Ins action.
Muzumdar et al.
PLoS One., 2009;4:e6334 -
A small molecule mimetic of the humanin peptide as a candidate for modulating NMDA-induced neurotoxicity.
Alam et al.
ACS Chem.Neurosci., 2018;9:462 -
Potent humanin analog increases glucose-stimulated Ins secretion through enhanced metabolism in the β cell.
Kuliawat et al.
FASEB J., 2013;27:4890
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Citation for HNGF6A
The citations listed below are publications that use Tocris products. Selected citations for HNGF6A include:
1 Citation: Showing 1 - 1
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A small molecule mimetic of the humanin peptide as a candidate for modulating NMDA-induced neurotoxicity.
Authors: Alam Et al.
ACS Chem.Neurosci. 2018;9:462
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