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ISAM 140

Catalog #: 5965 Datasheet / COA / SDS

Discontinued Product

5965 has been discontinued.
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ISAM 140 | CAS No. 932191-62-3 | Adenosine A2b Receptor Antagonists
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Description: High affinity A2B receptor antagonist

Chemical Name: 4-(2-Furanyl)-4,10-dihydro-2-methylpyrimido[1,2-a]benzimidazole-3-carboxylic acid-1-methylethyl ester

Purity: ≥98%

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Biological Activity

ISAM 140 is a high affinity A2B receptor antagonist (Ki = 3.49 nM). Exhibits >1000-fold selectivity for A2B over A1, A2A and A3 receptors.

Technical Data

M.Wt:
337.37
Formula:
C19H19N3O3
Solubility:
Soluble to 20 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
932191-62-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Discovery of potent and highly selective A2B adenosine receptor antagonist chemotypes.
    El Maatougui et al.
    J.Med.Chem., 2016;59:1967

Product Datasheets

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