MNITMT
Chemical Name: 4-Methyl-3-[(1-methyl-4-nitro-1H-imidazol-5-yl)thio]-4H-1,2,4-triazole
Purity: ≥99%
Biological Activity
MNITMT is a novel, non-toxic immunosuppressive agent. Inhibits human mixed lymphocyte reaction in vitro (ED50 = 2.7 μM) and prolongs skin graft survival in mice. Produces a 98.1% reduction in antibody response following oral administration in rabbits.Previously sold as Cat. No. 0564.
Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Additional Information
- Previously sold as Cat. No. 0564
Background References
-
Rational design of novel immunosuppressive drugs: analogues of azathio. lacking the 6-mercaptopurine substituent retain or have enhanced immunosuppressive effects.
Crawford et al.
J.Med.Chem., 1996;39:2690 -
Comparison of the effects of azathio. and its novel non-mercaptopurine analog on antibody response in rabbits.
Al-Safi et al.
Pol.J.Pharmacol., 2003;55:239
Product Datasheets
Reconstitution Calculator
Molarity Calculator
FAQs
No product specific FAQs exist for this product, however you may
View all Small Molecule FAQsReviews for MNITMT
There are currently no reviews for this product. Be the first to review MNITMT and earn rewards!
Have you used MNITMT?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
