Naloxonazine dihydrochloride
Chemical Name: Bis-[5-α-4,5-Epoxy-3,14-dihydroxy-17-(2-propenyl)-morphinan-6-ylidene] hydrazine dihydrochloride
Purity: ≥98%
Biological Activity
Naloxonazine dihydrochloride is a potent opioid antagonist, selective for μ1 receptors.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Differential blockade by naloxonazine of two μ opiate actions: analgesic and inhibition of gastrointestinal transit.
Paul et al.
Eur.J.Pharmacol., 1988;149:403
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Citations for Naloxonazine dihydrochloride
The citations listed below are publications that use Tocris products. Selected citations for Naloxonazine dihydrochloride include:
4 Citations: Showing 1 - 4
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Endogenous central amygdala mu-opioid receptor signaling promotes sodium appetite in mice.
Authors: Smith Et al.
Proc Natl Acad Sci U S A 2016;113:13893
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Pronociceptive and Antinociceptive Effects of Bupren. in the Spinal Cord Dorsal Horn Cover a Dose Range of Four Orders of Magnitude.
Authors: Gerhold Et al.
J Neurosci 2015;35:9580
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Low-frequency electroacupuncture suppresses focal epilepsy and improves epilepsy-induced sleep disruptions.
Authors: Yi Et al.
BMC Cell Biol 2015;22:49
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Prostatic relaxation induced by loperamide is reduced in spontaneously hypertensive rats.
Authors: Lee Et al.
J Biomed Sci 2012;2012:941685
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