Suplatast tosylate
Chemical Name: [3-[[4-(3-Ethoxy-2-hydroxypropoxy)phenyl]amino]-3-oxopropyl]dimethylsulfonium 4-methylbenzenesulfonate
Purity: ≥99%
Biological Activity
Suplatast tosylate is a th2 cytokine inhibitor that attenuates IL-2, IL-5 and IL-13 production and has no effect on IFN-γ production. Acts as an immunoregulator that suppresses IgE production, eosinophil infiltration and histamine release. Exhibits antiasthmatic, anti-inflammatory and antifibrotic activity in vivo and is orally active.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
-
Suppressive effects of anti-allergic agent suplatast tosilate (IPD-1151T) on the expression of co-stimulatory molecules on mouse splenocytes in vivo.
Kurokawa et al.
Mediators Inflamm., 2001;10:333 -
The effects of suplatast tosilate (IPD-1151T) on innate immunity and antigen-presenting cells.
Hsu et al.
Transpl.Immunol., 2007;18:108 -
Suplatast tosilate prevents bleomycin-induced pulmonary fibrosis in mice.
Furonaka et al.
J.Pharmacol.Exp.Ther., 2009;328:55
Product Datasheets
Reconstitution Calculator
Molarity Calculator
FAQs
No product specific FAQs exist for this product, however you may
View all Small Molecule FAQsReviews for Suplatast tosylate
There are currently no reviews for this product. Be the first to review Suplatast tosylate and earn rewards!
Have you used Suplatast tosylate?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
