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Estropipate

Catalog #: 3588 Datasheet / COA / SDS

Discontinued Product

3588 has been discontinued.
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Estropipate | CAS No. 7280-37-7 | Estrogen and Related Receptor Agonists
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Description: Estrogen receptor agonist and OATP1B1 inhibitor

Chemical Name: Piperazine estrone sulfate

Purity: ≥97%

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Biological Activity

Estrogen receptor agonist. Also inhibits organic anion transporting polypeptide 1B1 (OATP1B1) (IC50= 70 nM).

Technical Data

M.Wt:
436.56
Formula:
C18H22O5S.C4H10N2
Solubility:
Soluble to 5 mM in water and to 100 mM in DMSO
Purity:
≥97%
Storage:
Store at RT
CAS No:
7280-37-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Estrogen regulation of the cytochrome P450 3A subfamily in humans.
    Williams et al.
    J.Pharmacol.Exp.Ther., 2004;311:728
  2. A cell-based high-throughput assay to identify inhibitors of organic anion transporting polypeptides 1B1 and 1B3.
    Obaidat et al.
    FASEB J., 2009;23:748

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⚠ WARNING: This product can expose you to chemicals including Estropipate, which is known to the State of California to cause reproductive toxicity with developmental effects. For more information, go to www.P65Warnings.ca.gov

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