16 results for "Estrogen and Related Receptor Agonists" in Products
Estrogen and Related Receptor Agonists
The GPER (G protein-coupled estrogen receptor, GPR30) is a membrane protein that binds estrogen leading to estrogen-mediated adenylyl cyclase stimulation. The receptor is widely distributed in neural, breast, placental, heart, ovarian, prostate, hepatic, vascular epithelial and lymphoid tissues. The GPER binds estradiol with high affinity, but has lower affinity for the other estrogens, estrone and estriol. The receptor acts independently of ERα and ERβ and triggers ER-dependent EGFR action.
Estrogen receptor antagonist
| Alternate Names: | Fulvestrant |
| Chemical Name: | 7α,17β-[9-[(4,4,5,5,5-Pentafluoropentyl)sulfinyl]nonyl]estra-1,3,5(10)-triene-3,17-diol |
| Purity: | ≥98% |
Subtype-selective ERα agonist
| Chemical Name: | 4,4',4''-(4-Propyl-[1H]-pyrazole-1,3,5-triyl)trisphenol |
| Purity: | ≥98% |
Highly potent ERβ agonist
| Alternate Names: | Diarylpropionitrile |
| Chemical Name: | 2,3-bis(4-Hydroxyphenyl)-propionitrile |
| Purity: | ≥98% |
Non-selective PI 3-kinase inhibitor
| Chemical Name: | 2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-1-benzopyran-4-one |
| Purity: | ≥98% |
Endogenous ER agonist
| Alternate Names: | 17 β-Estradiol |
| Chemical Name: | (17β)-Estra-1,3,5(10)-triene-3,17-diol |
| Purity: | ≥98% |
Potent and selective GPER agonist
| Chemical Name: | (±)-1-[(3aR*,4S*,9bS*)-4-(6-Bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolin-8-yl]- ethanone |
| Purity: | ≥98% |
Estrogen receptor partial agonist/antagonist
| Chemical Name: | (Z)-2-[4-(1,2-Diphenyl-1-butenyl)phenoxy]-N,N-dimethylethanamine citrate |
| Purity: | ≥98% |
EGFR kinase inhibitor. Also estrogen and PPARγ ligand
| Chemical Name: | 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one |
| Purity: | ≥98% |
Agonist selective for estrogen-related receptors ERRβ and ERRγ
| Chemical Name: | N-(4-(Diethylaminobenzylidenyl)-N'-(4-hydroxybenzoyl)-hydrazine |
| Purity: | ≥98% |
LXR agonist; also ER partial agonist
| Alternate Names: | 27 OHC,27 HC |
| Chemical Name: | (3β,25R)-Cholest-5-ene-3,26-diol |
| Purity: | ≥95% |
Potent ERβ agonist
| Chemical Name: | 7-Ethenyl-2-(3-fluoro-4-hydroxyphenyl)-5-benzoxazolol |
| Purity: | ≥98% |
Endogenous estrogen receptor agonist
| Chemical Name: | (17α)-Estra-1,3,5(10)-triene-3,17-diol |
| Purity: | ≥97% |
Potent and selective ERβ agonist; neuroprotective
| Chemical Name: | 4-[4,4-Difluoro-1-(2-fluorophenyl)cyclohexyl]phenol |
| Purity: | ≥98% |
Estrogen-related receptor γ agonist; promotes maturation of hiPSC-derived cardiomyocytes
| Chemical Name: | 2-[2-(4-Bromophenyl)-1H-benzimidazol-6-yl]-2,3-dihydro-5-(4-morpholinyl)-1H-isoindol-1-one |
| Purity: | ≥98% |
Potent G protein-coupled estrogen receptor (GPER) agonist
| Chemical Name: | N-[2-Cyclohexyl-4-(1-methylethyl)phenyl]-5-(tetrahydro-2H-pyran-2-yl)-2-furanmethanamine |
| Purity: | ≥98% |
Potent pan-ERR agonist
| Chemical Name: | (E)-4-Hydroxy-N'-(naphthalen-2-ylmethylene)benzohydrazide |
| Purity: | ≥98% |
