Human FABP1/L-FABP ELISA Kit

Newer Version Available: Z-007
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Discontinued Product

Z-001 has been discontinued and is replaced by Z-007.

Product Details
Citations (4)
FAQs
Reviews

Human FABP1/L-FABP ELISA Kit Summary

Sample Type & Volume Required Per Well
Urine (25 uL)
Sensitivity
3 ng/mL
Assay Range
6.3 - 400 ng/mL
Cross-reactivity
< 0.5% cross-reactivity observed with available related molecules.< 50% cross-species reactivity observed with species tested.
Interference
No significant interference observed with available related molecules.

Product Summary

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: FABP1/L-FABP

Fatty Acid Binding Protein 1, also known as liver FABP, is a cytoplasmic transporter for long chain fatty acids, oxidized/peroxidized fatty acids, cholesterol, heme, Vitamin K, steroids, acyl CoA, leukotrienes, and prostaglandins. It is expressed by hepatocytes, simple columnar epithelium of the small intestine, and renal proximal tubule epithelium. FABP1 trafficks between the cytosol, peroxisomes, and nucleus. It delivers fatty acid cargo to the transcription factor PPAR alpha, leading to increased production of enzymes involved in the beta-oxidation of fatty acids. FABP1 also plays a role in the formation of prechylomicron vesicles by the endoplasmic reticulum.

Long Name:
Fatty Acid-Binding Protein 1
Entrez Gene IDs:
2168 (Human); 14080 (Mouse); 24360 (Rat)
Alternate Names:
FABP1; FABPL; fatty acid binding protein 1, liver; fatty acid-binding protein, liver; LFABP; L-FABP; L-FABPFatty acid-binding protein 1; Liver-type fatty acid-binding protein

Citations for Human FABP1/L-FABP ELISA Kit

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

4 Citations: Showing 1 - 4
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  1. Levels of protein C and soluble thrombomodulin in critically ill patients with acute kidney injury: a multicenter prospective observational study.
    Authors: Bouchard J, Malhotra R, Shah S, Kao Y, Vaida F, Gupta A, Berg D, Grinnell B, Stofan B, Tolwani A, Mehta R
    PLoS ONE, 2015-03-19;10(3):e0120770.
    Species: Human
    Sample Types: Urine
  2. A composite urine biomarker reflects interstitial inflammation in lupus nephritis kidney biopsies.
    Authors: Zhang X, Nagaraja HN, Nadasdy T
    Kidney Int., 2011-10-12;81(4):401-6.
    Species: Human
    Sample Types: Urine
  3. Urinary L-FABP and anaemia: distinct roles of urinary markers in type 2 diabetes.
    Authors: von Eynatten M, Baumann M, Heemann U
    Eur. J. Clin. Invest., 2009-11-11;40(2):95-102.
    Species: Human
    Sample Types: Urine
  4. Urinary excretion of liver type fatty acid binding protein accurately reflects the degree of tubulointerstitial damage.
    Authors: Yokoyama T, Kamijo-Ikemori A, Sugaya T, Hoshino S, Yasuda T, Kimura K
    Am. J. Pathol., 2009-05-12;174(6):2096-106.
    Species: Transgenic Mouse
    Sample Types: Tissue Homogenates, Urine

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