Obesity is an excessive accumulation of adipose tissue (body fat) which negatively impacts general health. A sedentary lifestyle and excessive calorie consumption are the most direct causes of obesity. However, polymorphisms in genes that influence appetite and metabolism are also believed to increase the risk of obesity. Long term obesity has been associated with the development of many diseases, including cardiovascular disorders, type-2 diabetes, liver disease, osteoarthritis, and thrombosis. R&D Systems offers a range of quality products to study the biological processes underlying obesity, including control of appetite, lipid and cholesterol metabolism, fatty acid transport, and other aspects of adipose tissue biology.