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Human Periostin/OSF-2 DuoSet ELISA

Catalog #: DY3548E
24 Citations Datasheet / COA / SDS

Discontinued Product

DY3548E has been discontinued.
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Human Periostin / OSF-2 ELISA Standard Curve
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Citations (24)
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Human Periostin/OSF-2 DuoSet ELISA Summary

Specificity
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* Provided that the recommended microplates, buffers, diluents, substrates and solutions are used, and the assay is run as summarized in the Assay Procedure provided.

Scientific Data

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Human Periostin / OSF-2 ELISA Standard Curve

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Preparation and Storage

Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: Periostin/OSF-2

Periostin, also known as OSF-2, is a secreted matricellular protein with functions in extracellular matrix formation, cell migration, and inflammation. It is secreted as a 90 kDa monomer that can aggregate into >170 kDa higher-order multimers. Periostin is expressed by mesenchymal cells such as vascular smooth muscle cells, fibroblasts, osteoblasts, and odontoblasts in developing teeth. It is upregulated in many carcinomas. Periostin binds to multiple Integrins and enhances cell adhesion and cell migration. It enhances Fibronectin and Collagen I production and promotes collagen fibrillogenesis. It also induces epithelial-mesenchymal transition, tumor growth, invasion, and metastasis. Periostin induces the expression of VEGF R2 on endothelial cells and VEGF-C in tumor cells, and it can induce tumor lymphangiogenesis. Periostin plays an important role in heart valve development and tissue healing after myocardial infarction. In asthma, it is upregulated in bronchial epithelium and plays both destructive and protective roles by inducing eosinophil infiltration and inhibiting goblet cell metaplasia and mucus production.

Long Name:
Osteoblast Specific Factor 2
Entrez Gene IDs:
10631 (Human); 50706 (Mouse); 361945 (Rat)
Alternate Names:
Fasciclin I-like; MGC119510; MGC119511; OSF2; OSF-2; OSF-2osteoblast specific factor 2 (fasciclin I-like); OSF2periodontal ligament-specific periostin; Osteoblast-specific factor 2; PDLPOSTN; periostin isoform thy2; periostin isoform thy4; periostin isoform thy6; periostin isoform thy8; Periostin; periostin, osteoblast specific factor; PNRP11-412K4.1; POSTN; TRIF52

Citations for Human Periostin/OSF-2 DuoSet ELISA

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

24 Citations: Showing 1 - 10
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  1. Nasal TSLP and periostin in infants with severe bronchiolitis and risk of asthma at 4�years of age
    Authors: ML Garcia-Gar, B Sastre, M Arroyas, M Beato, P Alonso, JM Rodrigo-Mu, V Del Pozo, I Casas, C Calvo
    Respiratory Research, 2023-01-24;24(1):26.
    Species: Human
    Sample Types: Nasopharyngeal aspirate
  2. Periostin Augments Vascular Smooth Muscle Cell Calcification via beta-Catenin Signaling
    Authors: I Alesutan, LA Henze, B Boehme, TTD Luong, D Zickler, B Pieske, KU Eckardt, A Pasch, J Voelkl
    Biomolecules, 2022-08-21;12(8):.
    Species: Human
    Sample Types: Serum
  3. Soluble POSTN is a novel biomarker complementing CA153 and CEA for breast cancer diagnosis and metastasis prediction
    Authors: L Jia, G Li, N Ma, A Zhang, Y Zhou, L Ren, D Dong
    BMC Cancer, 2022-07-12;22(1):760.
    Species: Human
    Sample Types: Cell Culture Supernates
  4. Serum Periostin Level and Genetic Polymorphisms Are Associated with Vertebral Fracture in Chinese Postmenopausal Women
    Authors: YM Guo, JH Cheng, H Zhang, JW He, H Yue, WW Hu, JM Gu, YQ Hu, WZ Fu, C Wang, ZL Zhang
    Genes, 2022-02-27;13(3):.
    Species: Human
    Sample Types: Serum
  5. Application of QPLEXTM biomarkers in cognitively normal individuals across a broad age range and diverse regions with cerebral amyloid deposition
    Authors: D Lee, JC Park, KS Jung, J Kim, JS Jang, S Kwon, MS Byun, D Yi, G Byeon, G Jung, YK Kim, DY Lee, SH Han, I Mook-Jung
    Experimental & Molecular Medicine, 2022-01-20;0(0):.
    Species: Human
    Sample Types: Plasma
  6. Involvement of the extracellular matrix proteins periostin and tenascin C in nasal polyp remodeling by regulating the expression of MMPs
    Authors: K Du, M Wang, N Zhang, P Yu, P Wang, Y Li, X Wang, L Zhang, C Bachert
    Clinical and translational allergy, 2021-09-06;11(7):e12059.
    Species: Human
    Sample Types: Tissue Homogenates
  7. Pathological Roles and Clinical Usefulness of Periostin in Type 2 Inflammation and Pulmonary Fibrosis
    Authors: J Ono, M Takai, A Kamei, Y Azuma, K Izuhara
    Biomolecules, 2021-07-22;11(8):.
    Species: Human
    Sample Types: Serum
  8. Expression profile of the matricellular protein periostin in paediatric inflammatory bowel disease
    Authors: T Coelho, E Sonnenberg, Y Gao, E Mossotto, A Khojanazar, A Griffin, S Mukanova, A Ashimkhano, R Haggarty, A Borissenko, JJ Ashton, IS Stafford, A Batra, NA Afzal, MP Stanton, B Vadgama, K Adrisova, RM Beattie, AP Williams, S Ennis, D Riethmache
    Scientific Reports, 2021-03-18;11(1):6194.
    Species: Human
    Sample Types: Plasma
  9. The potential pathways underlying the association of propyl-paraben exposure with aeroallergen sensitization and EASI score using metabolomics analysis
    Authors: Y Lee, E Lee, DK Yon, HM Jee, HS Baek, SW Lee, JY Cho, MY Han
    Scientific Reports, 2021-02-12;11(1):3772.
    Species: Human
    Sample Types: Serum
  10. iPSC-Derived Hereditary Breast Cancer Model Reveals the BRCA1-Deleted Tumor Niche as a New Culprit in Disease Progression
    Authors: L Portier, C Desterke, D Chaker, N Oudrhiri, A Asgarova, F Dkhissi, AG Turhan, A Bennaceur-, F Griscelli
    International Journal of Molecular Sciences, 2021-01-27;22(3):.
    Species: Human
    Sample Types: Cell Culture Supernates
  11. The vitamin D analogue calcipotriol promotes an anti-tumorigenic phenotype of human pancreatic CAFs but reduces T cell mediated immunity
    Authors: L Gorchs, S Ahmed, C Mayer, A Knauf, C Fernández, M Svensson, R Heuchel, E Rangelova, P Bergman, H Kaipe
    Sci Rep, 2020-10-15;10(1):17444.
    Species: Human
    Sample Types: Cell Culture Supernates
  12. Efficacy of endoscopic sinus surgery for eosinophilic chronic rhinosinusitis with asthma
    Authors: N Ohta, Y Suzuki, H Ikeda, N Noguchi, R Kakuta, T Suzuki, R Ikeda, M Yamazaki, Y Saito, Y Kusano, Y Ishida, F Shoji, H Yoshioka, J Ono, T Takahashi, Y Nakamura, I Ohno, K Izuhara
    Allergol Int, 2019-09-05;0(0):.
    Species: Human
    Sample Types: Serum
  13. A multiplex immunoassay of serum biomarkers for the detection of uveal melanoma
    Authors: J Song, SL Merbs, LJ Sokoll, DW Chan, Z Zhang
    Clin Proteomics, 2019-03-05;16(0):10.
  14. Bone Marrow Mesenchymal Stromal Cell-Derived Periostin Promotes B-ALL Progression by Modulating CCL2 in Leukemia Cells
    Authors: Z Ma, X Zhao, M Deng, Z Huang, J Wang, Y Wu, D Cui, Y Liu, R Liu, G Ouyang
    Cell Rep, 2019-02-05;26(6):1533-1543.e4.
    Species: Human
    Sample Types: Plasma
  15. Elevated serum periostin level in patients with chronic cough and airway hyperresponsiveness
    Authors: Y Kono, M To, R Tsuzuki, K Haruki, Y To
    Respir Investig, 2018-12-12;57(2):122-125.
    Species: Human
    Sample Types: Serum
  16. IL-13 induces periostin and eotaxin expression in human primary alveolar epithelial cells: Comparison with paired airway epithelial cells
    Authors: Y Ito, R Al Mubarak, N Roberts, K Correll, W Janssen, J Finigan, R Mishra, HW Chu
    PLoS ONE, 2018-04-19;13(4):e0196256.
    Species: Human
    Sample Types: Cell Culture Supernates
  17. Mixed Th2 and non-Th2 inflammatory pattern in the asthma-COPD overlap: a network approach
    Authors: LP de Llano, BG Cosío, A Iglesias, N de Las Cue, JJ Soler-Cata, JL Izquierdo, JL López-Camp, C Calero, V Plaza, M Miravitlle, A Torrego, E Martinez-M, JB Soriano, AL Viña, I Bobolea
    Int J Chron Obstruct Pulmon Dis, 2018-02-12;13(0):591-601.
    Species: Human
    Sample Types: Serum
  18. Asthma-COPD overlap is not a homogeneous disorder: further supporting data
    Authors: L Pérez-de-L, BG Cosio
    Respir. Res., 2017-11-02;18(1):183.
    Species: Human
    Sample Types: Serum
  19. Cigarette smoke differentially affects IL-13-induced gene expression in human airway epithelial cells
    Authors: TCJ Mertens, AM van der Do, LE Kistemaker, DK Ninaber, C Taube, PS Hiemstra
    Physiol Rep, 2017-07-11;5(13):.
    Species: Human
    Sample Types: Cell Culture Supernates
  20. Activated hepatic stellate cells secrete periostin to induce stem cell-like phenotype of residual hepatocellular carcinoma cells after heat treatment
    Authors: R Zhang, RR Yao, JH Li, G Dong, M Ma, QD Zheng, DM Gao, JF Cui, ZG Ren, RX Chen
    Sci Rep, 2017-05-19;7(1):2164.
    Species: Human
    Sample Types: Cell Culture Supernates
  21. Therapeutic Effect of Novel Single-Stranded RNAi Agent Targeting Periostin in Eyes with Retinal Neovascularization
    Authors: T Nakama, S Yoshida, K Ishikawa, Y Kubo, Y Kobayashi, Y Zhou, S Nakao, T Hisatomi, Y Ikeda, K Takao, K Yoshikawa, A Matsuda, J Ono, S Ohta, K Izuhara, A Kudo, KH Sonoda, T Ishibashi
    Mol Ther Nucleic Acids, 2017-02-09;6(0):279-289.
    Species: Human
    Sample Types: Cell Culture Supernates
  22. Circulating periostin in relation to insulin resistance and nonalcoholic fatty liver disease among overweight and obese subjects
    Sci Rep, 2016-11-25;6(0):37886.
    Species: Human
    Sample Types: Serum
  23. Urinary Periostin Excretion Predicts Renal Outcome in IgA Nephropathy
    Authors: Chun Soo Lim
    Am. J. Nephrol., 2016-11-01;44(6):481-492.
    Species: Human
    Sample Types: Urine
  24. Polycyclic aromatic hydrocarbons reciprocally regulate IL-22 and IL-17 cytokines in peripheral blood mononuclear cells from both healthy and asthmatic subjects.
    Authors: Ple C, Fan Y, Ait Yahia S, Vorng H, Everaere L, Chenivesse C, Balsamelli J, Azzaoui I, de Nadai P, Wallaert B, Lazennec G, Tsicopoulos A
    PLoS ONE, 2015-04-10;10(4):e0122372.
    Species: Human
    Sample Types: Cell Culture Supernates

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