Kaliotoxin
Discontinued Product
Biological Activity
Potent blocker of voltage-sensitive K+ channels (IC50 values are 0.1, 1.1 and 25 nM for KV1.3, KV1.1 and KV1.2 channels) respectively). Also inhibits Ca2+-activated K+ channels.Technical Data
(Modifications: Disulfide bridge between 8 - 28, 14 - 33, 18 - 35)
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
-
Synthesis and characterization of kaliotoxin: is the 26-32 sequence essential for potassium channel recognition?
Romi et al.
J.Biol.Chem., 1993;268:26302 -
Distribution in rat brain of binding sites of kaliotoxin, a blocker of Kv1.1and Kv1.3 α-subunits.
Mourre et al.
J.Pharmacol.Exp.Ther., 1999;291:943 -
High-resolution 3D structure determination of kaliotoxin by solid-state NMR spectroscopy.
Korukottu et al.
PLoS ONE, 2008;3:e2359
Product Datasheets
Reconstitution Calculator
Molarity Calculator
FAQs
No product specific FAQs exist for this product, however you may
View all Peptide FAQsReviews for Kaliotoxin
There are currently no reviews for this product. Be the first to review Kaliotoxin and earn rewards!
Have you used Kaliotoxin?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
