Rosmarinic acid

Name: Rosmarinic acid
Brand: Tocris Bioscience
SKU: 0630

Catalog #: 0630 Datasheet / COA / SDS

Discontinued Product

0630 has been discontinued.

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Rosmarinic acid | CAS No. 20283-92-5 | Antiviral Compounds

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Description: GPR35 agonist; anti-inflammatory, cytostatic and antiviral

Chemical Name: [R-(+)]-α-[[3-(3,4-Dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-3,4-dihydroxybenzenepropanoic acid

Purity: ≥99%

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Biological Activity

Anti-inflammatory, cytostatic and antiviral. Also displays agonist activity at GPR35.

Technical Data

M.Wt:

360.32

Formula:

C₁₈H₁₆O₈

Solubility:

Soluble to 100 mM in water

Purity:

≥99%

Storage:

Store at RT

CAS No:

20283-92-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

Multiple tyrosine metabolites are GPR35 agonists.
Deng et al.
Sci.Rep., 2012;2:373
Rosmarinic acid inhibits external oxidative effects of human polymorphonuclear granulocytes.
Van Kessel et al.
Agents Actions., 1986;17:375
Modification of endotoxin-induced haemodynamic and haematological changes in the rabbit by methylprednisolone, F(ab')₂ fragments and rosmarinic acid.
Bult et al.
Br.J.Pharmacol., 1985;84:317
Complement-dependent stimulation of prostacyclin biosynthesis: inhibition by rosmarinic acid.
Rampart et al.
Biochem.Pharmacol., 1986;35:1397
Inhibition of complement by covalent attachment of rosmarinic acid to activated C3b.
Sahu et al.
Biochem.Pharmacol., 1999;57:1439

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