Antiviral Compounds: Products

Inhibits hepatitis C viral life cycle; also α-crystallin (cryAB) chaperone

Toll-like receptor 7 (TLR7) agonist

Selective PC-PLC inhibitor

Potent and selective VPAC2 agonist

Specific inhibitor of NF-κB activation

Selective CCR5 antagonist

Viral RNA-dependent RNA polymerase (RdRP) inhibitor; broad spectrum antiviral nucleotide prodrug

Potent MEK1 inhibitor. Also inhibits IκBα phosphorylation

Toll-like receptor 7 (TLR7) agonist

Selective reverse transcriptase inhibitor; antiretroviral

Core binding factor inhibitor; attenuates hematopoiesis

mSTING agonist; induces antitumor immunological responses

HIV-1 and HIV-2 protease inhibitor

Potent and selective HIV-1 and HIV-2 protease inhibitor

Coronavirus PLpro inhibitor

Inosine monophosphatase dehydrogenase (IMPDH) inhibitor

Selective inhibitor of Akt/PKB signaling. Antitumor and antiviral

BLT1/BLT2 receptor agonist and potent chemotactic factor

Chemokine receptor 5 (CCR5) antagonist

Inhibits viral DNA polymerase; antiherpetic agent

α-glucosidase I and II inhibitor; also inhibits ceramide-specific glycosyltransferases and exhibits broad spectrum antiviral activity

p53 activator. Also ROS scavenger

Proapoptotic; downregulates PLK1 expression and activates mitochondrial Ca2+ uniporter

Reverse transcriptase inhibitor

Potent HIV-1 protease inhibitor

Non-nucleoside reverse transcriptase inhibitor

HIV protease inhibitor

Blocks eIF4E activity; antiviral guanosine analog

Potent CXCR4 antagonist

Inhibis HIV-1 replication in vitro; nucleoside analog

2,3-Oxidosqualene cyclase (OSC) inhibitor; blocks cholesterol synthesis

Potent and selective PI 4-kinase IIIβ inhibitor

DNA polymerase α, δ and ε inhibitor

Potent and selective CCR5 and CCR2 chemokine receptor antagonist

Promotes Akt hyperphosphorylation; decreases phosphorylation of Akt substrates

Antiflaviviral; active against Zika, Dengue and Hepatitis C viruses

Highly potent CXCR4 antagonist; inhibits HIV-1 replication

Potent and selective hepatitis B virus inhibitor

Potent LSD1 inhibitor

Potent and selective PI 4-kinase IIIβ inhibitor; broad spectrum enterovirus replication inhibitor

Oligosaccharyltransferase (OST) inhibitor; anti-flaviviral

Hepatitis C virus (HCV) protease NS3/4A inhibitor

PTEN inhibitor; induces necroptosis; anti-inflammatory

Inhibitor of HCV RNA-dependent RNA polymerase (RdRP; NS5b); potent hepatitis C virus (HCV) replication inhibitor

STAT5-SUMO protein-protein interaction inhibitor

Highly potent and selective HIV-1 protease inhibitor

Potent influenza virus neuraminidase inhibitor

Potent and selective Src tyrosine kinase family inhibitor; anticancer; antiviral; orally bioavailable

SKP2 (S-phase kinase-associated protein 2) inhibitor; upregulates p27 and arrests cell cycle in G1 phase

Influenza virus neuraminidase inhibitor; antiviral prodrug