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RNA polymerase inhibitor; inhibits replication of a broad range of RNA and DNA viruses, including SARS-CoV-2 and Zika
SARS-CoV and SARS-CoV-2 PLpro inhibitor
Binds to SARS-CoV-2 frameshifting element and reduces frameshifting efficiency
SARS-CoV-2 PLpro and replication inhibitor
Potent coronavirus helicase inhibitor; also inhibits human papillomavirus E6
Selective exportin-1 (XPO1/CRM1) inhibitor
Prodrug of antiviral nucleoside analog; inhibits SARS-CoV, SARS-CoV-2 and MERS-CoV infection
Non-nucleoside reverse transcriptase inhibitor
Potent hepatitis C virus (HCV) NS3 protease inihibitor
Selective exportin 1 (XPO1/CRM1) inhibitor
Glutathione (GSH) precursor; maintains stem cell function in culture.
SARS-CoV-2 main protease fluorescent ligand; TR-FRET acceptor
SARS-CoV-2 Mpro Degrader (PROTAC®)