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SBP1-FITC

Catalog #: 7232 Datasheet / COA / SDS

Discontinued Product

7232 has been discontinued.
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SBP1-FITC
1 Image
Description: Fluorescent ACE2-derived peptide; binds receptor binding domain of SARS-CoV-2 spike protein

Purity: ≥95%

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Biological Activity

SBP1-FITC is a fluorescently labelled peptide derived from human ACE2 (SBP1, Cat. No. 7233). Composed of SBP1 conjugated to FITC (Fluorescein-5-isothiocyanate; Cat. No. 5440). SBP1 binds receptor binding domain (RBD) of insect-derived SARS-CoV-2 spike protein (KD = 1.3 μM for N-terminal biotinylated, insect-derived spike protein RBD; see Zhang et al preprint publication).

Please note - unpublished, in-house data suggests SBP1 has approximately 75-fold lower affinity for insect-derived SARS-CoV-2 RBD than reported by Zhang et al.

Technical Data

M.Wt:
3438.68
Formula:
C159H217N33O51S
Sequence:
IEEQAKTFLDKFNHEAEDLFYQS

(Modifications: Ile-1 = FITC-PEG4-Ile, Ser-23 = C-terminal amide)

Solubility:
Soluble to 1 mg/ml in 0.1M PBS (pH 7.4)
Purity:
≥95%
Storage:
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. The first-in-class peptide binder to the SARS-CoV-2 spike protein.
    Zhang et al.
    BioRxiv - Paper not yet peer reviewed, 2020;

Product Datasheets

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Reconstitution Calculator

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