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SBP1

Catalog #: 7233 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
7233/1
SBP1
1 Image
Description: ACE2 derived peptide; binds SARS-CoV-2 spike protein receptor binding domain

Purity: ≥95%

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Biological Activity

SBP1 is a human ACE2 receptor-derived 23-amino acid peptide. Binds receptor binding domain (RBD) of insect-derived SARS-CoV-2 spike protein (KD = 1.3 μM for N-terminal biotinylated, insect-derived spike protein RBD; see Zhang et al preprint publication).

Please note - unpublished, in-house data suggests approximately 75-fold lower affinity for insect-derived SARS-CoV-2 RBD than reported by Zhang et al.

Technical Data

M.Wt:
2802.05
Formula:
C127H185N31O41
Sequence:
IEEQAKTFLDKFNHEAEDLFYQS

(Modifications: Ser-23 = C-terminal amide)

Solubility:
Soluble to 1 mg/ml in PBS
Purity:
≥95%
Storage:
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Investigation of ACE2 N-terminal fragments binding to SARS-CoV-2 Spike RBD.
    Zhang et al.
    BioRxiv - Paper not yet peer reviewed, 2020;

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