Platelets are produced in the bone marrow, where they bud off of mature megakaryocytes in response to thrombopoetin. Also known as thrombocytes, platelets play a critical role in hemostasis, the formation of blood clots to prevent excessive blood loss. Platelets become activated and promote coagulation in response to collagen released from damaged endothelial cells that line the surface of blood vessels. By secreting a number of growth factors such as platelet-derived growth factor (PDGF) and vascular endothelial growth factor (VEGF), platelets can contribute to wound healing. Low numbers of platelets (thrombocytopenia) can increase vulnerability to bleeding, whereas high platelet counts (thrombocytosis) can lead to thrombosis-induced heart attack or stroke.
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PRODUCT AVAILABILITY: Update Regarding the Evolving COVID-19 Situation
Bio-Techne appreciates the critical role that you and our products and services play in research efforts to further scientific innovation and discovery. We are continually assessing our manufacturing and supplier capabilities during the COVID-19 situation and are implementing precautionary measures to ensure uninterrupted supply of products and services. Currently, and as we abide by local shelter in place orders across the world, we are fully operational and do not anticipate any material supply disruptions across our Bio-Techne brands and product lines. As the situation evolves, our goal is to utilize preventive measures to reduce the threat that COVID-19 poses to our ability to meet the needs of our customers globally.